4-chloro-6,7-dimethoxyquinoline
- CAS NO.:35654-56-9
- Empirical Formula: C11H10ClNO2
- Molecular Weight: 223.66
- MDL number: MFCD07778437
- EINECS: 676-028-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-12-26 17:07:23
What is 4-chloro-6,7-dimethoxyquinoline?
Chemical properties
Light brown powder
The Uses of 4-chloro-6,7-dimethoxyquinoline
4-Chloro-6,7-dimethoxyquinoline, can be used as an intermediate for the synthesis of various pharmaceutical and biologically active compounds. It is used for the preparation of Tivozanib (T447205), and Cabozantinib (C051500), acting as anticancer agents.
What are the applications of Application
4-chloro-6,7-dimethoxy-quinoline can be rich for Buddhist nun with for Wo Zhani medicine as preparing antitumor drug card The key intermediate of thing molecule synthesis.
Synthesis
With 3,4-dimethoxyaniline is raw material, obtains aniline compound through nitrification, iron powder reducing, then with Ethyl chloroformate, in Feldalat NM condition cyclization, prepares 4-hydroxyquinoline compounds, after through three Chlorethoxyfos chloro obtains 4-chloro-6,7-dimethoxy-quinoline.
Properties of 4-chloro-6,7-dimethoxyquinoline
Melting point: | 132.0 to 136.0 °C |
Boiling point: | 325.2±37.0 °C(Predicted) |
Density | 1.265±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 3.95±0.30(Predicted) |
color | Pale Brown to Light Brown |
InChI | InChI=1S/C11H10ClNO2/c1-14-10-5-7-8(12)3-4-13-9(7)6-11(10)15-2/h3-6H,1-2H3 |
CAS DataBase Reference | 35654-56-9(CAS DataBase Reference) |
Safety information for 4-chloro-6,7-dimethoxyquinoline
Computed Descriptors for 4-chloro-6,7-dimethoxyquinoline
InChIKey | WRVHQEYBCDPZEU-UHFFFAOYSA-N |
SMILES | N1C2C(=CC(OC)=C(OC)C=2)C(Cl)=CC=1 |
Abamectin manufacturer
VGS SYNTHESIS PRIVATE LIMITED
Vepan Pharmatech Pvt Ltd
Sintilla Medcoms Pvt Ltd
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
You may like
-
35654-56-9 4-Chloro-6,7-dimethoxyquinoline 98%View Details
35654-56-9 -
35654-56-9 99%View Details
35654-56-9 -
4-Chloro-6,7-dimethoxyquinoline 35654-56-9 98%View Details
35654-56-9 -
4-Chloro-6,7-dimethoxy-quinoline 98%View Details
-
4-Chloro-6,7-dimethoxyquinoline carboxylic AcidView Details
35654-56-9 -
4-Chloro-6,7-dimethoxyquinoline 99%View Details
35654-56-9 -
4-Chloro-6,7-dimethoxyquinoline CAS 35654-56-9View Details
35654-56-9 -
4-chloro-6,7-dimethoxyquinoline CASView Details