4-chloro-6,7-dimethoxyquinoline
- CAS NO.：35654-56-9
- Empirical Formula: C11H10ClNO2
- Molecular Weight: 223.66
- MDL number: MFCD07778437
- EINECS: 676-028-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-11 16:58:07
What is 4-chloro-6,7-dimethoxyquinoline?
Chemical properties
Light brown powder
The Uses of 4-chloro-6,7-dimethoxyquinoline
4-Chloro-6,7-dimethoxyquinoline, can be used as an intermediate for the synthesis of various pharmaceutical and biologically active compounds. It is used for the preparation of Tivozanib (T447205), and Cabozantinib (C051500), acting as anticancer agents.
What are the applications of Application
4-chloro-6,7-dimethoxy-quinoline can be rich for Buddhist nun with for Wo Zhani medicine as preparing antitumor drug card The key intermediate of thing molecule synthesis.
Synthesis
With 3,4-dimethoxyaniline is raw material, obtains aniline compound through nitrification, iron powder reducing, then with Ethyl chloroformate, in Feldalat NM condition cyclization, prepares 4-hydroxyquinoline compounds, after through three Chlorethoxyfos chloro obtains 4-chloro-6,7-dimethoxy-quinoline.
Properties of 4-chloro-6,7-dimethoxyquinoline
| Melting point: | 132.0 to 136.0 °C |
| Boiling point: | 325.2±37.0 °C(Predicted) |
| Density | 1.265±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.95±0.30(Predicted) |
| color | Pale Brown to Light Brown |
| InChI | InChI=1S/C11H10ClNO2/c1-14-10-5-7-8(12)3-4-13-9(7)6-11(10)15-2/h3-6H,1-2H3 |
| CAS DataBase Reference | 35654-56-9(CAS DataBase Reference) |
Safety information for 4-chloro-6,7-dimethoxyquinoline
Computed Descriptors for 4-chloro-6,7-dimethoxyquinoline
| InChIKey | WRVHQEYBCDPZEU-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC(OC)=C(OC)C=2)C(Cl)=CC=1 |
4-chloro-6,7-dimethoxyquinoline manufacturer
Sintilla Medcoms Pvt Ltd
1Y
Phone:+91-8886733867
Whatsapp: +91 8886733867
product: 4-Chloro-6,7-dimethoxy-quinoline 98%
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