4-AMINOPYRIMIDINE-5-CARBONITRILE

CAS NO.：16357-69-0
Empirical Formula: C5H4N4
Molecular Weight: 120.11
MDL number: MFCD00054552
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 4-AMINOPYRIMIDINE-5-CARBONITRILE?

Chemical properties

White to brown solid

The Uses of 4-AMINOPYRIMIDINE-5-CARBONITRILE

4-Amino-5-pyrimidinecarbonitrile may be used as a monodentate ligand to prepare metal complexes of Co(II), Ni(II), Cu(II) and Pd(II) ions. It may be used as a reactant to prepare 1H-pyrimido[4,5-d]pyrimidine-2,4-dione.

General Description

4-Amino-5-pyrimidinecarbonitrile (APC) is a pyrimidine derivative that has been synthesized via three-component reaction between benzaldehyde, benzamidine hydrochloride and malononitrile. The infrared, ¹H NMR, ¹³C NMR and mass spectra of APC have been recorded.

Properties of 4-AMINOPYRIMIDINE-5-CARBONITRILE

Melting point:	251-255 °C(lit.)
Boiling point:	355.8±27.0 °C(Predicted)
Density	1.34±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DCM, DMSO, DMF, Methanol
form	Powder
pka	2.60±0.10(Predicted)
color	Brown
Sensitive	Moisture Sensitive
CAS DataBase Reference	16357-69-0(CAS DataBase Reference)

Safety information for 4-AMINOPYRIMIDINE-5-CARBONITRILE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.