4-Acetylbenzonitrile
Synonym(s):4′-Cyanoacetophenone
- CAS NO.：1443-80-7
- Empirical Formula: C9H7NO
- Molecular Weight: 145.16
- MDL number: MFCD00001825
- EINECS: 215-885-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is 4-Acetylbenzonitrile?
Chemical properties
light yellow to yellow-beige crystalline mass or crystalline powder and chunks
The Uses of 4-Acetylbenzonitrile
4-Acetylbenzonitrile can be used in the preparation of antimalarial isonitriles.
The Uses of 4-Acetylbenzonitrile
4-Acetylbenzonitrile is used in the preparation of antimalarial isonitriles. It is also used for synthetic API such as anesthetic agents and anti-allergic agents.
Synthesis Reference(s)
The Journal of Organic Chemistry, 44, p. 1613, 1979 DOI: 10.1021/jo01324a006
Tetrahedron Letters, 28, p. 1345, 1987 DOI: 10.1016/S0040-4039(00)95366-8
General Description
The relaxation-assisted two-dimensional infrared (RA 2DIR) spectroscopy of 4-acetylbenzonitrile was analyzed.
Flammability and Explosibility
Not classified
Purification Methods
Recrystallise the nitrile from EtOH [Wagner et al. J Am Chem Soc 108 7727 1986]. [Beilstein 10 H 695, 10 III 3030.]
Properties of 4-Acetylbenzonitrile
| Melting point: | 56-59 °C(lit.) |
| Boiling point: | 95-96°C 14mm |
| Density | 1.1555 (rough estimate) |
| vapor pressure | 0.856Pa at 25℃ |
| refractive index | 1.4500 (estimate) |
| Flash point: | 95-96°C/14mm |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform |
| form | Crystalline Mass or Crystalline Powder and Chunks |
| color | Light yellow to yellow-beige |
| Water Solubility | Soluble in chloroform. Insoluble in water. |
| BRN | 1932887 |
| CAS DataBase Reference | 1443-80-7(CAS DataBase Reference) |
Safety information for 4-Acetylbenzonitrile
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
Computed Descriptors for 4-Acetylbenzonitrile
4-Acetylbenzonitrile manufacturer
JSK Chemicals
3Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 4-Acetylbenzonitrile, 95% 1443-80-7 99%
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran
![4-(3-(5-[3,5-DI(TRIFLUOROMETHYL)PHENYL]-2-FURYL)ACRYLOYL)BENZONITRILE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB5261280.gif)
You may like
-
1443-80-7 99%View Details
1443-80-7 -
1443-80-7 4-Acetylbenzonitrile 98%View Details
1443-80-7 -
4-Acetylbenzonitrile 1443-80-7 98%View Details
1443-80-7 -
1443-80-7 98%View Details
1443-80-7 -
1443-80-7 98%View Details
1443-80-7 -
4-Acetylbenzonitrile, 99% CAS 1443-80-7View Details
1443-80-7 -
4'-Cyanoacetophenone CAS 1443-80-7View Details
1443-80-7 -
4-Acetylbenzonitrile CAS 1443-80-7View Details
1443-80-7
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.