4-ACETOXYBENZALDEHYDE

Synonym(s):4-Formylphenyl acetate

CAS NO.：878-00-2
Empirical Formula: C9H8O3
Molecular Weight: 164.16
MDL number: MFCD00003384
EINECS: 212-898-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 4-ACETOXYBENZALDEHYDE?

Chemical properties

Clear colorless to pale yellow liquid

The Uses of 4-ACETOXYBENZALDEHYDE

4-Acetoxybenzaldehyde is used as pharmaceutical intermediate.

Definition

ChEBI: An acetate ester that is phenyl acetate substituted by a formyl group at position 4.

Synthesis Reference(s)

The Journal of Organic Chemistry, 50, p. 539, 1985 DOI: 10.1021/jo00204a025

General Description

The reductive amination of 4-acetoxybenzaldehyde (4-formylphenyl acetate) with an azanonaborane cluster in the presence of H₃BNH₂(CH₂)₄NH₂ was studied.

Properties of 4-ACETOXYBENZALDEHYDE

Melting point:	213 °C
Boiling point:	152-153 °C/17 mmHg (lit.)
Density	1.168 g/mL at 25 °C (lit.)
refractive index	n20/D 1.538(lit.)
Flash point:	>230 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	clear liquid
Specific Gravity	1.168
color	Colorless to Light yellow
Sensitive	Air Sensitive
BRN	1101359
CAS DataBase Reference	878-00-2(CAS DataBase Reference)
EPA Substance Registry System	Benzaldehyde, 4-(acetyloxy)- (878-00-2)

Safety information for 4-ACETOXYBENZALDEHYDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.