4-(4-Chloro-2-thienyl)-2-thiazolamine

CAS NO.：570407-10-2
Empirical Formula: C7H5ClN2S2
Molecular Weight: 216.71
MDL number: MFCD24627156
EINECS: 1312995-182-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-07 18:44:46

What is 4-(4-Chloro-2-thienyl)-2-thiazolamine?

The Uses of 4-(4-Chloro-2-thienyl)-2-thiazolamine

4-(4-Chloro-2-thienyl)-2-thiazolamine can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis

Synthesis_570407-10-2
Bromine was added to an ether solution of 4-chloro-2-acetylthiophene under ice cooling, and the mixture was stirred at room temperature for 2 hours to obtain a brominated compound. Thiourea was added to an EtOH solution of the brominated compound at room temperature, and the mixture was stirred overnight at 80℃ to obtain 2-amino-4-(4-chlorothiophen-2-yl)thiazole.

Properties of 4-(4-Chloro-2-thienyl)-2-thiazolamine

Boiling point:	395.3±27.0 °C(Predicted)
Density	1.535±0.06 g/cm3(Predicted)
pka	3.47±0.10(Predicted)

Safety information for 4-(4-Chloro-2-thienyl)-2-thiazolamine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P330:Rinse mouth. P362:Take off contaminated clothing and wash before reuse. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…