4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE

CAS NO.：1511-16-6
Empirical Formula: C21H24Cl2FNO2
Molecular Weight: 412.33
MDL number: MFCD00673961
EINECS: 689-044-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 20:33:22

What is 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE?

The Uses of 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE

Haloperidol Hydrochloride is the salt analogue of Haloperidol (H103700) a dopamine inverse agonist, antidyskinetic and antipsychotic agent.

What are the applications of Application

Haloperidol hydrochloride is an inhibitor of D2DR, NMDA, and NOS1

Biological Activity

haloperidol hydrochloride is an antipsychotic drug that has similar actions to the antipsychotic medicine phenothiazine [1].haloperidol hydrochloride has been reported to play a role as an inverse agonist of dopamine. in addition, haloperidol hydrochloride has been found to be highlt potent neuroleptic by relieving nervous through the depression of nerve function. besides, haloperidol hydrochloride has shown about 50-fold potency than chiorpromazine, the other antipsychotic drug. haloperidol hydrochloride has shown beneficial effects in the treatment of delusions and hallucinations. these effects are mainly achieved through blockage of dopamine receptors in the mesocortex and limbic system. haloperidol hydrochloride has been revealed to prevent the effects of dopamine in the nigrostriatal pathways, which probably explains the associated side effects such as akathisia and dystonias[1].

storage

Room temperature

References

[1] dr ananya mandal, md .haloperidol pharmacology.

Properties of 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE

Melting point:	226-227.5°
storage temp.	Store at -20°C
solubility	insoluble in H2O; ≥10.31 mg/mL in DMSO; ≥2.96 mg/mL in EtOH with gentle warming and ultrasonic
form	solid

Safety information for 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE

Computed Descriptors for 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE

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