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HomeProduct name list4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE

4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE

4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE Structural

What is 4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE?

Definition

ChEBI: CGH 2466 is a member of thiazoles.

Biological Activity

Adenosine A 1 , A 2B and A 3 receptor antagonist (IC 50 values are 19, 21, and 80 nM respectively). Also inhibits p38 MAPK (IC 50 = 187-400 nM) and phosphodiesterase type 4D (IC 50 = 22 nM). Displays potent anti-inflammatory effects in vitro and in vivo . Potentially useful for asthma and chronic obstructive pulmonary disease (COPD) research.

Properties of 4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE

storage temp.  Desiccate at +4°C

Safety information for 4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE

Computed Descriptors for 4-(3,4-DICHLOROPHENYL)-5-(4-PYRIDINYL)-2-THIAZOLAMINE

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