(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
- CAS NO.:201856-57-7
- Empirical Formula: C18H25NO5
- Molecular Weight: 335.39
- MDL number: MFCD09751005
- EINECS: 1592732-453-0
- SAFETY DATA SHEET (SDS)
What is (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate?
The Uses of (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is used as a reagent in the synthesis of abeo-taxane derivatives that possess broad inhibitory effects against proliferation of colon cancer, melanoma, and renal cancer cell lines. (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is also used as a reagent in the synthesis of a novel D-ring modified Docetaxel (D494420) analogue which has proven to have equipotent cytotoxicity in relation to Paclitaxel (P132500) towards cancer cell lines.
Properties of (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
Boiling point: | 459.6±45.0 °C(Predicted) |
Density | 1.16 |
storage temp. | 2-8°C |
pka | -4.97±0.60(Predicted) |
CAS DataBase Reference | 201856-57-7(CAS DataBase Reference) |
Safety information for (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
Computed Descriptors for (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION XANTHAN GUM Racecadotril SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN Folic Acid Impurity G Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
(2S,3S)-methyl 3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropanoate
HLCSYHHJEMPKSY-RRKHLBDSSA-N
4-Dichloroethoxy-carbonyl docetaxel
2-Azetidinone, 3-hydroxy-4-phenyl-1-[(1S)-1-phenylethyl]-, (3R,4S)-
Docetaxel Impurity 15
7-Epi-docetaxel (Docetaxel Impurity C)
Paclitaxel
PIYPODQNLLWXJG-VHSXEESVSA-N
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