3′,4′-(Methylenedioxy)propiophenone

CAS NO.：28281-49-4
Empirical Formula: C10H10O3
Molecular Weight: 178.18
MDL number: MFCD00016652
EINECS: 248-937-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-25 16:21:11

What is 3′,4′-(Methylenedioxy)propiophenone?

Description

3′,4′-(Methylenedioxy)propiophenone, also known as 3,4-(Methylenedioxy)phenyl-1-propanone (MDP1P), is a member of the benzodioxole family, which is a five-membered heterocyclic compound. This compound is a phenylpropanoid found in some plants of the genus Piper and is an isomer of 3,4-methylenedioxyphenyl-2-propanone (MDP2P).

Chemical properties

Pale Orange Solid

The Uses of 3′,4′-(Methylenedioxy)propiophenone

Intermediate in the production of Isosafrole and Ethylone.

Definition

ChEBI: 3,4-Methylenedioxypropiophenone is a member of benzodioxoles.

What are the applications of Application

3′,4′-(Methylenedioxy)propiophenone is a synthetic compound with a fatty acid chain. It has been shown to have potent activity against leishmania and has been used as an intermediate in the synthesis of other drugs. 3′,4′-(Methylenedioxy)propiophenone can be synthesized by acylation reactions with chloride and acetylcholinesterase inhibition. This product also has molecular docking properties, which have been analyzed using computational methods, such as profiling and profile analysis.

Synthesis Reference(s)

Tetrahedron Letters, 23, p. 3085, 1982 DOI: 10.1016/S0040-4039(00)87539-5

Properties of 3′,4′-(Methylenedioxy)propiophenone

Melting point:	34-36°C
Boiling point:	165-168°C 20mm
Density	1,21 g/cm³
Flash point:	165-168°C/20mm
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Low-Melting Solid
color	Off-White to Light Brown
BRN	165729
InChI	InChI=1S/C10H10O3/c1-2-8(11)7-3-4-9-10(5-7)13-6-12-9/h3-5H,2,6H2,1H3
CAS DataBase Reference	28281-49-4(CAS DataBase Reference)

Safety information for 3′,4′-(Methylenedioxy)propiophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P233:Keep container tightly closed. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304:IF INHALED: P312:Call a POISON CENTER or doctor/physician if you feel unwell. P321:Specific treatment (see … on this label). P330:Rinse mouth. P340:Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362:Take off contaminated clothing and wash before reuse. P391:Collect spillage. Hazardous to the aquatic environment P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P403:Store in a well-ventilated place. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…