3,4-Methylenedioxyacetophenone

CAS NO.：3162-29-6
Empirical Formula: C9H8O3
Molecular Weight: 164.16
MDL number: MFCD00005831
EINECS: 221-613-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-08 20:25:11

What is 3,4-Methylenedioxyacetophenone?

Chemical properties

Colorless or white crystals. M.P. 89℃. Almost insoluble in water, soluble in alcohol and oils.

The Uses of 3,4-Methylenedioxyacetophenone

3?,4?-(Methylenedioxy)acetophenone is used in the synthesis of N-ethyl-1-(3,4-methylenedioxyphenyl)ethylamine.

The Uses of 3,4-Methylenedioxyacetophenone

3′,4′-(Methylenedioxy)acetophenone was used in the synthesis of N-ethyl-1-(3,4-methylenedioxyphenyl)ethylamine.

Definition

ChEBI: 3,4-Methylenedioxyacetophenone is a member of benzodioxoles.

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 4507, 1957 DOI: 10.1021/ja01573a069

Synthesis

3,4-Methylenedioxyacetophenone's synthesis method: 1) from Piperonylic acid plus Acetic acid vapors at high temperature over catalyst (Thoria, e.g.). 2) from alpha-Methylpiperonylic acid by oxidation.

Properties of 3,4-Methylenedioxyacetophenone

Melting point:	87-89 °C(lit.)
Boiling point:	152-155°C 15mm
Density	1.2132 (rough estimate)
refractive index	1.5260 (estimate)
Flash point:	152-155°C/15mm
storage temp.	Inert atmosphere,Room Temperature
form	Crystalline Powder
color	Beige
Odor	Heavy, sweet-floral and warm-herbaceous odor
Water Solubility	Slightly soluble in water.
BRN	139669
CAS DataBase Reference	3162-29-6(CAS DataBase Reference)
NIST Chemistry Reference	3',4'-(Methylenedioxy)acetophenone(3162-29-6)

Safety information for 3,4-Methylenedioxyacetophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.