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HomeProduct name list3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE

3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE

Synonym(s):3,4-Dihydroxy-N-methyl-N-nitrosoaniline

  • Empirical Formula: C7H8N2O3
  • Molecular Weight: 168.15
  • MDL number: MFCD01076450
  • Update Date: 2023-04-23 13:52:06
3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE Structural

What is 3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE?

The Uses of 3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE

Methyl-3,4-dephostatin has been used as:

  • an inhibitor for methyltransferases
  • a kinase-related inhibitor for human transglutaminase
  • a cysteine binding compound for screening its effect on C-terminal domain (CTD) of human immunodeficiency virus (HIV-1) capsid protein

What are the applications of Application

3,4-Dephostatin is a protein tyrosine phosphatase inhibitor

Biochem/physiol Actions

Methyl-3,4-dephostatin is a tyrphostin-related compound isolated from Streptomyces MJ742-NF5 strain. It favors nerve growth factor-based neurite formation in pheochromocytoma PC12 cells. Being a stable analog of the nitrosoaniline dephostatin, it can mimic phosphotyrosine substrate for Tyrosyl-DNA phosphodiesterase I (TdpI).

Properties of 3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE

storage temp.  2-8°C
solubility  DMSO: 18 mg/mL, soluble
form  powder
color  red-brown

Safety information for 3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE

Computed Descriptors for 3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE

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