3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE
- CAS NO.：90897-92-0
- Empirical Formula: C6H3BrF2Mg
- Molecular Weight: 217.29
- MDL number: MFCD00672004
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE?
Chemical properties
Tan liquid
The Uses of 3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE
3,4-Difluorophenylmagnesium bromide, 0.50 M in 2-MeTHF is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
The Uses of 3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE
3,4-Difluorophenylmagnesium bromide can be used:
- To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.
- In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.
- In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.
- In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.
Properties of 3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE
| Boiling point: | 65 °C |
| Density | 0.965 g/mL at 25 °C |
| Flash point: | 1 °F |
| storage temp. | 2-8°C |
| form | Solution |
| color | Yellow to dark brown |
| Water Solubility | Reacts with water. |
| Sensitive | Air & Moisture Sensitive |
Safety information for 3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H302:Acute toxicity,oral H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for 3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE
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