3-TRIMETHYLSILYL-2-PROPYN-1-OL
Synonym(s):3-(Trimethylsilyl)-2-propyn-1-ol
- CAS NO.：5272-36-6
- Empirical Formula: C6H12OSi
- Molecular Weight: 128.24
- MDL number: MFCD00002913
- EINECS: 226-094-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 3-TRIMETHYLSILYL-2-PROPYN-1-OL?
Chemical properties
clear yellow liquid
The Uses of 3-TRIMETHYLSILYL-2-PROPYN-1-OL
Trimethylsilylpropargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.
Properties of 3-TRIMETHYLSILYL-2-PROPYN-1-OL
| Melting point: | 63.5-65.0 °C |
| Boiling point: | 76 °C11 mm Hg(lit.) |
| Density | 0.865 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 152 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Benzene (Sparingly) |
| form | Liquid |
| pka | 13.71±0.10(Predicted) |
| color | Clear yellow |
| Specific Gravity | 0.865 |
| Water Solubility | Not miscible with water. |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions |
| BRN | 1902505 |
| CAS DataBase Reference | 5272-36-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Trimethylsilylpropargyl alcohol(5272-36-6) |
| EPA Substance Registry System | 2-Propyn-1-ol, 3-(trimethylsilyl)- (5272-36-6) |
Safety information for 3-TRIMETHYLSILYL-2-PROPYN-1-OL
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H227:Flammable liquids H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P309:IF exposed or if you feel unwell: P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-TRIMETHYLSILYL-2-PROPYN-1-OL
| InChIKey | ZVGCJDPEKKEYES-UHFFFAOYSA-N |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
3-(Trimethylsilyl)propargyl alcohol CAS 5272-36-6View Details
5272-36-6 -
3-Trimethylsilyl-2-propyn-1-ol, 99% CAS 5272-36-6View Details
5272-36-6 -
3-Trimethylsilyl-2-propyn-1-ol CAS 5272-36-6View Details
5272-36-6 -
3-Trimethylsilylpropargyl Alcohol CAS 5272-36-6View Details
5272-36-6 -
3-(Trimethylsilyl)propargyl alcohol CAS 5272-36-6View Details
5272-36-6 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.