3-Quinuclidinol
Synonym(s):1-Azabicyclo[2.2.2]octan-3-ol;3-Hydroxyquinuclidine
- CAS NO.：1619-34-7
- Empirical Formula: C7H13NO
- Molecular Weight: 127.18
- MDL number: MFCD00151326
- EINECS: 216-578-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:42:50
What is 3-Quinuclidinol?
Chemical properties
Crystalline Solid
The Uses of 3-Quinuclidinol
3-Quinuclidinol acts as a chiral building block for various antimuscarinic agents and other active pharmaceutical ingredients. It serves as a catalyst for condensation of methyl vinyl ketone with aldehydes. It is also used as a reagent for cleavage of beta-keto and vinylogous beta-keto esters. Further, it plays an important role as a synthon in the preparation of cholinergic receptor ligands and anesthetics. In addition to this, it is used in chemoselective alfa-iodination of acrylic esters through Morita-Baylis-Hillman reaction.
The Uses of 3-Quinuclidinol
Hypotensive. Synthon for preparation of cholinergic receptor ligands and anesthetics
Definition
ChEBI: Quinuclidine in which a hydrogen atom at position 3 is substituted by a hydroxy group.
Hazard
Mutation.
Properties of 3-Quinuclidinol
| Melting point: | 220-223 °C(lit.) |
| Boiling point: | 235.98°C (rough estimate) |
| Density | 1.0083 (rough estimate) |
| refractive index | 1.4790 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acidic (Slightly), Chloroform (Sparingly), Methanol (Slightly) |
| pka | 14.75±0.20(Predicted) |
| form | Crystalline Powder |
| color | White to beige |
| Water Solubility | soluble |
| Sensitive | Air Sensitive |
| Merck | 14,8082 |
| BRN | 104327 |
| CAS DataBase Reference | 1619-34-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Quinuclidinol(1619-34-7) |
| EPA Substance Registry System | 1-Azabicyclo[2.2.2]octan-3-ol (1619-34-7) |
Safety information for 3-Quinuclidinol
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Quinuclidinol
Abamectin manufacturer
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%View Details
99903-60-3 -
88491-46-7 98%View Details
88491-46-7 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.