3-PHENYL-1,1,1-TRIFLUOROPROPAN-2-ONE

CAS NO.：350-92-5
Empirical Formula: C9H7F3O
Molecular Weight: 188.15
MDL number: MFCD00068171
EINECS: 626-575-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3-PHENYL-1,1,1-TRIFLUOROPROPAN-2-ONE?

Chemical properties

clear colorless to light yellow liquid

Synthesis Reference(s)

Journal of Medicinal Chemistry, 42, p. 3315, 1999 DOI: 10.1021/jm980734a
Tetrahedron Letters, 28, p. 4259, 1987 DOI: 10.1016/S0040-4039(00)96479-7
The Journal of Organic Chemistry, 54, p. 661, 1989 DOI: 10.1021/jo00264a029

General Description

1,1,1-Trifluoro-3-phenyl-2-propanone is a trifluoromethyl ketone. Its in vitro neuroprotective potency against low K(+)-induced apoptosis in cerebellar granule neurons (CGNs) by different pathways has been reported.

Properties of 3-PHENYL-1,1,1-TRIFLUOROPROPAN-2-ONE

Boiling point:	51-52 °C2 mm Hg(lit.)
Density	1.22 g/mL at 25 °C(lit.)
refractive index	n20/D 1.444(lit.)
Flash point:	91 °F
storage temp.	Sealed in dry,Room Temperature
color	Clear, faint yellow
BRN	2614467
CAS DataBase Reference	350-92-5(CAS DataBase Reference)

Safety information for 3-PHENYL-1,1,1-TRIFLUOROPROPAN-2-ONE

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02
GHS Hazard Statements	H226:Flammable liquids
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge.