3-HYDROXYBENZOPHENONE

CAS NO.：13020-57-0
Empirical Formula: C13H10O2
Molecular Weight: 198.22
MDL number: MFCD00002297
EINECS: 235-879-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3-HYDROXYBENZOPHENONE?

Chemical properties

light beige to brown-grey crystalline powder

The Uses of 3-HYDROXYBENZOPHENONE

3-Hydroxybenzophenone is a benzophenone metabolite with potential estrogenic and anti-androgenic activity. is a more attractive hydrogen bonding co-material for MCPBA, as the 3-hydroxyl group is unable to form an intramolecular hydrogen bond. It is commonly used as a radical and cationic photo initiators.

Preparation

Preparation by aromatization of 5-benzoyl-2- cyclohexenone,
? in the presence of 10% Pd/C in refluxing xylene for 6 h (60%)
? in the presence of lithium bromide and cupric bromide in refluxing acetonitrile for 1 h (75%).

Properties of 3-HYDROXYBENZOPHENONE

Melting point:	113-115 °C (lit.)
Boiling point:	295.53°C (rough estimate)
Density	1.1184 (rough estimate)
refractive index	1.5954 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	Soluble in Chloroform, DCM. Ethyl Acetate.
form	Solid
pka	9.18±0.10(Predicted)
color	White
λmax	315nm(EtOH)(lit.)
CAS DataBase Reference	13020-57-0(CAS DataBase Reference)
NIST Chemistry Reference	M-hydroxybenzophenone(13020-57-0)

Safety information for 3-HYDROXYBENZOPHENONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.