3-Dimethylaminophenol

Synonym(s):N,N-Dimethyl-3-aminophenol

CAS NO.：99-07-0
Empirical Formula: C8H11NO
Molecular Weight: 137.18
MDL number: MFCD00002264
EINECS: 202-727-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 16:48:35

What is 3-Dimethylaminophenol?

Chemical properties

Brown to Purple Solid

The Uses of 3-Dimethylaminophenol

3-Dimethylaminophenol can be used as neostigmine bromide intermediate and dye intermediate.

General Description

Needles (from ligroin) or a dark gray solid.

Air & Water Reactions

Sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

An amine and phenol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Phenols do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid.

Fire Hazard

Flash point data for 3-Dimethylaminophenol are not available. 3-Dimethylaminophenol is probably combustible.

Properties of 3-Dimethylaminophenol

Melting point:	82-84 °C(lit.)
Boiling point:	265-268°C
Density	1.0976 (rough estimate)
refractive index	1.5895 (estimate)
Flash point:	148 °C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	10.06±0.10(Predicted)
form	Powder
color	violet
PH	7 (10g/l, H2O, 20℃)(slurry)
Water Solubility	SLIGHTLY SOLUBLE
Sensitive	Light Sensitive
BRN	774631
Stability:	Stable. May be air-sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference	99-07-0(CAS DataBase Reference)
NIST Chemistry Reference	Phenol, 3-(dimethylamino)-(99-07-0)
EPA Substance Registry System	m-(Dimethylamino)phenol (99-07-0)

Safety information for 3-Dimethylaminophenol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.