3-CHLORO-6-METHOXYPYRIDAZINE

CAS NO.：1722-10-7
Empirical Formula: C5H5ClN2O
Molecular Weight: 144.56
MDL number: MFCD00006467
EINECS: 217-019-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3-CHLORO-6-METHOXYPYRIDAZINE?

The Uses of 3-CHLORO-6-METHOXYPYRIDAZINE

3-Chloro-6-methoxypyridazine was used in the preparation of number of α-aryl-α-(pyridazin-3-yl)-acetonitriles.

Synthesis Reference(s)

The Journal of Organic Chemistry, 60, p. 1466, 1995 DOI: 10.1021/jo00110a059

General Description

3-Chloro-6-methoxypyridazine undergoes regioselective metallation using various lithium alkylamides, temperatures and solvents (THF and ether). It was lithiated using lithium 2,2,6,6-tetramethylpiperidide during the synthesis of minaprine.

Properties of 3-CHLORO-6-METHOXYPYRIDAZINE

Melting point:	84-85 °C(lit.)
Boiling point:	285℃
Density	1.292
Flash point:	126℃
storage temp.	Inert atmosphere,Room Temperature
form	powder to crystal
pka	0.74±0.10(Predicted)
color	White to Almost white
BRN	118854
InChI	InChI=1S/C5H5ClN2O/c1-9-5-3-2-4(6)7-8-5/h2-3H,1H3
CAS DataBase Reference	1722-10-7(CAS DataBase Reference)

Safety information for 3-CHLORO-6-METHOXYPYRIDAZINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.