3-Bromo-5-hydroxypyridine
- CAS NO.：74115-13-2
- Empirical Formula: C5H4BrNO
- Molecular Weight: 174
- MDL number: MFCD00661305
- EINECS: 627-764-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-15 19:19:13
What is 3-Bromo-5-hydroxypyridine?
Chemical properties
Light yellow needles
Effects
3-Bromo-5-hydroxypyridine is a nicotinic acetylcholine receptor ligand that has been shown to be an analog of acetylcholine. It binds to the nicotinic acetylcholine receptors, which are found in the neuromuscular junction and autonomic ganglia.
The Uses of 3-Bromo-5-hydroxypyridine
3-Bromo-5-hydroxypyridine can be used as a probe for studying the function of acetylcholine receptors. This drug has also been shown to have anti-tumor activity in vivo and to inhibit the growth of tumor cells in vitro. It inhibits cancer cell proliferation by binding to the cholinergic receptor on tumor cells and interfering with its function.
Properties of 3-Bromo-5-hydroxypyridine
| Melting point: | 166-170 °C |
| Boiling point: | 343.7±22.0 °C(Predicted) |
| Density | 1.788±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 8.37±0.10(Predicted) |
| color | White to tan |
| Water Solubility | Slightly soluble in water. Soluble in chloroform and ethyl acetate. |
| InChI | InChI=1S/C5H4BrNO/c6-4-1-5(8)3-7-2-4/h1-3,8H |
| CAS DataBase Reference | 74115-13-2(CAS DataBase Reference) |
Safety information for 3-Bromo-5-hydroxypyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Bromo-5-hydroxypyridine
| InChIKey | VNYBIBSZZDAEOK-UHFFFAOYSA-N |
| SMILES | C1=NC=C(Br)C=C1O |
3-Bromo-5-hydroxypyridine manufacturer
SGT life sciences
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VITAL SYNTHETICLABS PVT LTD
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ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED
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Sintilla Medcoms Pvt Ltd
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Rivashaa Agrotech Biopharma Pvt. Ltd.
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CSR Laboratories Pvt Ltd
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Madin Life Sciences Pvt Ltd
1Y
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