3-Aminopropyltriethoxysilane
Synonym(s):3-(Triethoxysilyl)propylamine;3-Triethoxysilylpropylamine;APTES;APTS
- CAS NO.：919-30-2
- Empirical Formula: C9H23NO3Si
- Molecular Weight: 221.37
- MDL number: MFCD00008207
- EINECS: 213-048-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:32
What is 3-Aminopropyltriethoxysilane?
Chemical properties
Colorless transparent liquid
The Uses of 3-Aminopropyltriethoxysilane
Forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. Used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.
The Uses of 3-Aminopropyltriethoxysilane
(3-Aminopropyl)triethoxysilane is useful in the formation of aminopropyl derivative of glass. It acts as an adsorbent for affinity chromatography. It is used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures. In addition, it is used as adhesives and sealant chemicals, paint additives and coating additives. Further, it is used as a silylation reagent for coating glass and silica surfaces and to crosslink and immobilize proteins and other molecules.
What are the applications of Application
(3-Aminopropyl)triethoxysilane is an adhesion promoter and adsorbent for affinity chromatography
General Description
(3-Aminopropyl)tiethoxysilane (APTES) is used as an amino-silane which is mainly used as a dispersant. APTES attaches an amino group to the functional silane for bio-conjugation.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
(3-Aminopropyl)triethoxysilane forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. It is used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.
Safety Profile
Poison by intraperitoneal route.Moderately toxic by ingestion and skin contact. A skin andeye irritant. When heated to decomposition it emits toxicfumes of NOx.
Properties of 3-Aminopropyltriethoxysilane
| Melting point: | -70 °C |
| Boiling point: | 217 °C(lit.) |
| Density | 0.946 g/mL at 25 °C(lit.) |
| vapor pressure | 0-7910Pa at 25℃ |
| refractive index | n |
| Flash point: | 205 °F |
| storage temp. | room temp |
| solubility | Miscible with toluene, acetone, chloroform and ethanol. |
| form | Liquid |
| pka | 10.37±0.10(Predicted) |
| Specific Gravity | 0.942 |
| color | APHA: ≤25 |
| PH | 11 (20g/l, H2O, 20℃) |
| explosive limit | 0.8-4.5%(V) |
| Water Solubility | REACTS |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| BRN | 1754988 |
| Stability: | Stable. Incompatible with acids, strong oxidizing agents. May decompose on exposure to moisture. |
| CAS DataBase Reference | 919-30-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Propanamine, 3-(triethoxysilyl)-(919-30-2) |
| EPA Substance Registry System | 3-Aminopropyltriethoxysilane (919-30-2) |
Safety information for 3-Aminopropyltriethoxysilane
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Aminopropyltriethoxysilane
| InChIKey | WYTZZXDRDKSJID-UHFFFAOYSA-N |
3-Aminopropyltriethoxysilane manufacturer
Covalent Incorporation
Shree Ganesh Life Sciences (Shree Ganesh Group)
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