3-Aminopropyltriethoxysilane

Synonym(s):3-(Triethoxysilyl)propylamine;3-Triethoxysilylpropylamine;APTES;APTS

CAS NO.：919-30-2
Empirical Formula: C9H23NO3Si
Molecular Weight: 221.37
MDL number: MFCD00008207
EINECS: 213-048-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-31 18:15:48

What is 3-Aminopropyltriethoxysilane?

Chemical properties

Colorless transparent liquid

The Uses of 3-Aminopropyltriethoxysilane

Forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. Used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.

The Uses of 3-Aminopropyltriethoxysilane

(3-Aminopropyl)triethoxysilane is useful in the formation of aminopropyl derivative of glass. It acts as an adsorbent for affinity chromatography. It is used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures. In addition, it is used as adhesives and sealant chemicals, paint additives and coating additives. Further, it is used as a silylation reagent for coating glass and silica surfaces and to crosslink and immobilize proteins and other molecules.

What are the applications of Application

(3-Aminopropyl)triethoxysilane is an adhesion promoter and adsorbent for affinity chromatography

General Description

(3-Aminopropyl)tiethoxysilane (APTES) is used as an amino-silane which is mainly used as a dispersant. APTES attaches an amino group to the functional silane for bio-conjugation.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

(3-Aminopropyl)triethoxysilane forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. It is used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.

Safety Profile

Poison by intraperitoneal route.Moderately toxic by ingestion and skin contact. A skin andeye irritant. When heated to decomposition it emits toxicfumes of NOx.

Properties of 3-Aminopropyltriethoxysilane

Melting point:	-70 °C
Boiling point:	217 °C(lit.)
Density	0.946 g/mL at 25 °C(lit.)
vapor pressure	0-7910Pa at 25℃
refractive index	n20/D 1.422
Flash point:	205 °F
storage temp.	room temp
solubility	Miscible with toluene, acetone, chloroform and ethanol.
form	Liquid
pka	10.37±0.10(Predicted)
Specific Gravity	0.942
color	APHA: ≤25
PH	11 (20g/l, H2O, 20℃)
explosive limit	0.8-4.5%(V)
Water Solubility	REACTS
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	7: reacts slowly with moisture/water
BRN	1754988
Stability:	Stable. Incompatible with acids, strong oxidizing agents. May decompose on exposure to moisture.
CAS DataBase Reference	919-30-2(CAS DataBase Reference)
NIST Chemistry Reference	1-Propanamine, 3-(triethoxysilyl)-(919-30-2)
EPA Substance Registry System	3-Aminopropyltriethoxysilane (919-30-2)

Safety information for 3-Aminopropyltriethoxysilane

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H314:Skin corrosion/irritation H317:Sensitisation, Skin
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.