Ethyl (3-fluorobenzoyl)acetate
Synonym(s):(m-Fluorobenzoyl)acetic acid ethyl ester;3-(3-Fluorophenyl)-3-oxopropanoic acid ethyl ester;3-(3-Fluorophenyl)-3-oxo-propionic acid ethyl ester;Ethyl m-fluorobenzoyl acetate;Ethyl 2-3-fluorobenzoylacetate
- CAS NO.：33166-77-7
- Empirical Formula: C11H11FO3
- Molecular Weight: 210.2
- MDL number: MFCD03424809
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-10-25 15:33:13
What is Ethyl (3-fluorobenzoyl)acetate?
The Uses of Ethyl (3-fluorobenzoyl)acetate
Reactant for:
- Preparation of biologically active molecules
Synthesis
To a stirring suspension of NaH and CO(OEt)2 in toluene was added dropwise a solution of substituted acetophenone in toluene under reflux. The mixture was allowed to reflux and was stirred for 20 min after the addition was complete. When cooled to room temperature, the mixture was acidified with glacial HOAc. After ice-cold water was added, the mixture was extracted with toluene. The extract was then dried over anhydrous MgS04. After the toluene was evaporated in vacuo to give the corresponding substituted Ethyl (3-fluorobenzoyl)acetate.
Properties of Ethyl (3-fluorobenzoyl)acetate
| Boiling point: | 262-263 °C(lit.) |
| Density | 1.166 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 10.10±0.46(Predicted) |
| form | Liquid |
| color | Colorless to orange |
| CAS DataBase Reference | 33166-77-7(CAS DataBase Reference) |
Safety information for Ethyl (3-fluorobenzoyl)acetate
Computed Descriptors for Ethyl (3-fluorobenzoyl)acetate
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
Ethyl (3-fluorobenzoyl)acetate 98.00% CAS 33166-77-7View Details
33166-77-7 -
1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%View Details
99903-60-3 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.