(2S,4R)-4-METHYLGLUTAMIC ACID
- CAS NO.：31137-74-3
- Empirical Formula: C6H11NO4
- Molecular Weight: 161.16
- MDL number: MFCD00937765
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is (2S,4R)-4-METHYLGLUTAMIC ACID?
Chemical properties
White
The Uses of (2S,4R)-4-METHYLGLUTAMIC ACID
A highly selective and potent agonist for kainate receptors.
What are the applications of Application
(2S,4R)-4-Methylglutamic Acid is a kainate receptor agonist and EAAT2 inhibitor
Biological Activity
Potent and highly selective kainate receptor agonist, with an IC 50 for inhibition of [ 3 H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. Also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™ and Kainate Receptor Tocriset™ .
Properties of (2S,4R)-4-METHYLGLUTAMIC ACID
| Melting point: | 178 °C |
| Boiling point: | 287.44°C (rough estimate) |
| Density | 1.3482 (rough estimate) |
| refractive index | 1.4230 (estimate) |
| storage temp. | Store at RT |
| solubility | H2O: >10 mg/mL |
| form | solid |
| pka | 2.34±0.21(Predicted) |
| color | white |
| CAS DataBase Reference | 31137-74-3(CAS DataBase Reference) |
Safety information for (2S,4R)-4-METHYLGLUTAMIC ACID
Computed Descriptors for (2S,4R)-4-METHYLGLUTAMIC ACID
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![(+/-)-1-AMINOCYCLOPENTANE-TRANS-1,3-DICARBOXYLIC ACID, [4,5-3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB0357960.gif)
You may like
-
1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%View Details
99903-60-3 -
88491-46-7 98%View Details
88491-46-7 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.