N-Stearoyl-phytosphingosine
- CAS NO.：34354-88-6
- Empirical Formula: C36H73NO4
- Molecular Weight: 583.97
- MDL number: MFCD02259296
- EINECS: 812-962-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-28 18:20:31
What is N-Stearoyl-phytosphingosine?
Description
N-Stearoyl-phytosphingosine (SPS), sphingolipids frequently found in mammalian skin, plants, and yeast, have been used in cosmetics. In mice, treatment with SPS inhibited histamine-induced scratching behavior and vascular permeability. This agent inhibited the expression of the allergic cytokines IL-4 and TNF-a and the activation of the transcription factors NF-jB and c-jun in histamine-stimulated skin tissues[1].
The Uses of N-Stearoyl-phytosphingosine
An intercellular lipid that benefits skin hydration and protects against SLS irritation.
What are the applications of Application
N-Stearoyl Phytosphingosine is an intercellular lipid
Definition
ChEBI: N-octadecanoyl-4-hydroxysphinganine is a phytoceramide in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl). It is a N-acylphytosphingosine and a N-stearoyl-sphingoid base.
References
[1] Kwon-Ryeol Ryu. “Anti-scratching Behavioral Effects of N-Stearoyl-phytosphingosine and 4-Hydroxysphinganine in Mice.” Lipids 45 7 (2010): 613–618.
Properties of N-Stearoyl-phytosphingosine
| Melting point: | 122-124°C |
| Boiling point: | 718℃ at 10hPa |
| Density | 0.994-1.014 at 20℃ |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform : Methanol = 3 : 1 (Slightly), Pyridine (Slightly, Heated, Sonicated) |
| form | Solid |
| color | White to Off-White |
Safety information for N-Stearoyl-phytosphingosine
Computed Descriptors for N-Stearoyl-phytosphingosine
| InChIKey | IEZRNEGTKRQRFV-LFBNJJMOSA-N |
| SMILES | C(N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC)(=O)CCCCCCCCCCCCCCCCC |
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