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HomeProduct name list2H-1,2,4-Triazole-3-carboxamide

2H-1,2,4-Triazole-3-carboxamide

Synonym(s):1H-1,2,4-Triazole-3-carboxamide

2H-1,2,4-Triazole-3-carboxamide Structural

What is 2H-1,2,4-Triazole-3-carboxamide?

The Uses of 2H-1,2,4-Triazole-3-carboxamide

N-Des-1-β-D-ribofuranosyl Ribavirin (Ribavirin EP Impurity D) is an impurity in the synthesis of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.

Definition

ChEBI: 1,2,4-triazole-3-carboxamide is a member of the class of triazoles that is 1H-1,2,4-triazole substituted by an aminocarbonyl group at position 3. It is the major catabolite and aglycon of ribavirin. It has a role as a human urinary metabolite and a drug metabolite. It is a member of triazoles, a primary carboxamide, a monocarboxylic acid amide and an aromatic amide.

Properties of 2H-1,2,4-Triazole-3-carboxamide

Melting point: 315 °C
Boiling point: 393.4±25.0 °C(Predicted)
Density  1.537±0.06 g/cm3(Predicted)
storage temp.  Inert atmosphere,Room Temperature
solubility  Aqueous Base (Slightly), DMSO (Slightly)
form  Solid
pka 8.50±0.20(Predicted)
color  White to Off-White
CAS DataBase Reference 3641-08-5(CAS DataBase Reference)

Safety information for 2H-1,2,4-Triazole-3-carboxamide

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H332:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2H-1,2,4-Triazole-3-carboxamide

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