2,8-Quinolinediol
Synonym(s):2,8-Dihydroxyquinoline
- CAS NO.:15450-76-7
- Empirical Formula: C9H7NO2
- Molecular Weight: 161.16
- MDL number: MFCD00216696
- EINECS: 604-962-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:05
What is 2,8-Quinolinediol?
Chemical properties
Brown Powder
The Uses of 2,8-Quinolinediol
2,8-Quinolinediol is a substituted quinolinone derivative used in the preparation of pharmaceutical compounds.
The Uses of 2,8-Quinolinediol
2,8-Quinolinediol is suitable for use as standard in a study to identify the urinary metabolites for the toxicity related processes and pathogenesis induced by doxorubicin (DOX) to rats by online and off-line LC-MS techniques. It may be used as starting reagent for the preparation of two powerful β2-adrenergic receptor agonists, used for the treatment of asthma:
- Procaterol
- Indacaterol
Definition
ChEBI: Quinoline-2,8-diol is a dihydroxyquinoline. It is a tautomer of an 8-hydroxyquinolin-2(1H)-one.
General Description
2,8-Quinolinediol is a quinolone derivative. It has been reported as metabolite of 8-hydroxyquinoline-N-oxide in rabbits. Synthesis of 2,8-quinolinediol has been reported. It is reported as one of the six possible forms of 8-hydroxycarbostyril. It has been detected as new UV-absorbing compound (UAC) in cow milk and its structure was elucidated using HRMS and by 1H, 13C and 1H ×13C NMR.It is also known as 8-hydroxycarbostyril or 8-hydroxyquinolin-2(1H)-one.
Properties of 2,8-Quinolinediol
Melting point: | ~290 °C (dec.) |
Boiling point: | 403.2±45.0 °C(Predicted) |
Density | 1.337±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
form | Solid |
pka | 8.85±0.20(Predicted) |
color | Dark Reddish Brown |
λmax | 335nm(EtOH)(lit.) |
BRN | 472906 |
CAS DataBase Reference | 15450-76-7(CAS DataBase Reference) |
Safety information for 2,8-Quinolinediol
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,8-Quinolinediol
Abamectin manufacturer
ALKALI METALS LTD
Alchem Synthon Pvt Ltd
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