2,4-Dihydroxy-3-nitropyridine

CAS NO.：89282-12-2
Empirical Formula: C5H4N2O4
Molecular Weight: 156.1
MDL number: MFCD01075671
SAFETY DATA SHEET (SDS)
Update Date: 2023-11-03 09:50:52

What is 2,4-Dihydroxy-3-nitropyridine?

Chemical properties

Yellow powder

Reactions

2,4-Dihydroxy-3-nitropyridine could be quickly transformed into 5-bromo-2,4-dihydroxy-3-nitropyridine by the action of a solution of bromine. 3.5 g of 2,4-Dihydroxy-3-nitropyridine were heated with a mixture of 1.15 ml of bromine and 30 ml of acetic acid at 70℃ for 15 minutes. When the reaction mixture was cooled with ice, 3.7 g of 5-bromo-2,4-dihydroxy-3-nitropyridine separated out[1]. Yield: 70 %

References

[1] Kolder, C. R. , and H. J. D. Hertog . Migration of halogen atoms in halogeno-derivatives of 2,4-dihydroxypyridine (II). Recueil des Travaux Chimiques des Pays-Bas 72.10(2010):853-858.

Properties of 2,4-Dihydroxy-3-nitropyridine

Melting point:	265°C (dec.)
Boiling point:	305.6±42.0 °C(Predicted)
Density	1.65±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
form	powder to crystal
pka	4.50±1.00(Predicted)
color	Light yellow to Yellow to Green
BRN	149558
InChI	InChI=1S/C5H4N2O4/c8-3-1-2-6-5(9)4(3)7(10)11/h1-2H,(H2,6,8,9)
CAS DataBase Reference	89282-12-2(CAS DataBase Reference)

Safety information for 2,4-Dihydroxy-3-nitropyridine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.