2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone
Synonym(s):1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone
- CAS NO.:86404-63-9
- Empirical Formula: C10H7F2N3O
- Molecular Weight: 223.18
- MDL number: MFCD02093825
- EINECS: 617-850-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone?
Chemical properties
Pale Yellow Solid
The Uses of 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone
Antifungal activity, particularly toward Candida albicans and Candida parapsilosis
The Uses of 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone
2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (Voriconazole EP Impurity A; Voriconazole USP Related Compound C) is an antifungal activity, particularly toward Candida albicans and Candida parapsilosis
What are the applications of Application
2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone is shows antifungal activity, particularly toward Candida albicans and Candida parapsilosis
Properties of 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone
Melting point: | 103-107 °C(lit.) |
Boiling point: | 388.0±52.0 °C(Predicted) |
Density | 1.39±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | 2.05±0.10(Predicted) |
color | White to pale brown |
CAS DataBase Reference | 86404-63-9(CAS DataBase Reference) |
Safety information for 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone
2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone manufacturer
SHUBH LIFECARE
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Covalent Incorporation
1Y
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product: 86404-63-9 DFTA (2,4-DIFLUORO-ALPHA-(1H-1,2,4-TRIAZOLYL)ACETOPHENONE) (KEY INTERMEDIATE FOR FLUCONAZOLE) 98%
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product: 2',4'-Difluoro-2-(1H-1,2,4-triazol-1-yl)-acetophenone 98%
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New Products
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rac 5-Desfluoro Voriconazole
Voriconazole
Voriconazole Impurity 8
Voriconazole (2R,3R)-Isomer
2-Chloro-2',4'-difluoroacetophenone
Voriconazole N-Oxide
(2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
ent-Voriconazole
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