2,4-Diamino-6-hydroxypyrimidine
- CAS NO.：56-06-4
- Empirical Formula: C4H6N4O
- Molecular Weight: 126.12
- MDL number: MFCD00006098
- EINECS: 200-254-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 13:37:16
What is 2,4-Diamino-6-hydroxypyrimidine?
Description
2,4-
Chemical properties
White Solid
The Uses of 2,4-Diamino-6-hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical]
The Uses of 2,4-Diamino-6-hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.
storage
+4°C
Purification Methods
It recrystallises from H2O. [Beilstein 25 III/IV 3642.]
Properties of 2,4-Diamino-6-hydroxypyrimidine
| Melting point: | 285-286 °C (dec.) (lit.) |
| Boiling point: | 234.22°C (rough estimate) |
| Density | 1.3659 (rough estimate) |
| refractive index | 1.7990 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 10.61±0.50(Predicted) |
| form | Fine Crystalline Powder |
| color | White to cream |
| Sensitive | Light Sensitive |
| Merck | 14,2981 |
| BRN | 125006 |
| CAS DataBase Reference | 56-06-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 4(1H)-pyrimidinone, 2,6-diamino-(56-06-4) |
| EPA Substance Registry System | 2,6-Diamino-4(1H)-pyrimidinone (56-06-4) |
Safety information for 2,4-Diamino-6-hydroxypyrimidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 2,4-Diamino-6-hydroxypyrimidine
| InChIKey | SWELIMKTDYHAOY-UHFFFAOYSA-N |
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