2',3'-O-(2,4,6-TRINITROPHENYL) ADENOSINE 5'-TRIPHOSPHATE MONOLITHIUM TRISODIUM SALT

CAS NO.：61368-63-6
Empirical Formula: C22H14LiN11Na3O25P3
Molecular Weight: 1001.24
MDL number: MFCD08669665
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-18 11:31:08

What is 2',3'-O-(2,4,6-TRINITROPHENYL) ADENOSINE 5'-TRIPHOSPHATE MONOLITHIUM TRISODIUM SALT?

The Uses of 2',3'-O-(2,4,6-TRINITROPHENYL) ADENOSINE 5'-TRIPHOSPHATE MONOLITHIUM TRISODIUM SALT

TNP-ATP Triethylammonium Salt is a P2X receptor antagonist.

What are the applications of Application

TNP-ATP tetrasodium salt solution is a purinoceptor P2X2/3 antagonist

Definition

ChEBI: An organophosphate oxoanion arising from deprotonation of the triphosphate OH groups of TNP-ATP.

Biological Activity

High affinity, selective P2X receptor antagonist. Inhibits ATP-induced currents in cells expressing P2X 1 , P2X 3 and heteromeric P2X 2/3 receptors with IC 50 values of 6, 0.9 and 7 nM respectively. Displays 1000-fold selectivity over P2X 2 , P2X 4 and P2X 7 .

Properties of 2',3'-O-(2,4,6-TRINITROPHENYL) ADENOSINE 5'-TRIPHOSPHATE MONOLITHIUM TRISODIUM SALT

storage temp.	−20°C
solubility	H₂O: >20 mg/mL
form	solid
color	red to orange
Water Solubility	Soluble in water (supplied pre-dissolved at a concentration of 10mM)

Safety information for 2',3'-O-(2,4,6-TRINITROPHENYL) ADENOSINE 5'-TRIPHOSPHATE MONOLITHIUM TRISODIUM SALT

Computed Descriptors for 2',3'-O-(2,4,6-TRINITROPHENYL) ADENOSINE 5'-TRIPHOSPHATE MONOLITHIUM TRISODIUM SALT

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Related products of tetrahydrofuran

TNP-LPS (Lipopolysaccharide)

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

TNP2 (B-2)

TNP-CTP

2',3'-O-(2,4,6-Trinitro-2,5-cyclohexadien-1-ylidene)adenosine 5'-(tetrahydrogen triphosphate)

TNP-GDP

Guanosine 5'-(tetrahydrogen triphosphate), 2',3'-O-(2,4,6-trinitro-2,4-cyclohexadien-1-ylidene)-

TNP-GppNHp