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HomeProduct name list2'-O-Methylkurarinone

2'-O-Methylkurarinone

2'-O-Methylkurarinone Structural

What is 2'-O-Methylkurarinone?

The Uses of 2'-O-Methylkurarinone

2''-Methoxykurarinone can be used to determine the cytotoxic effects of flavonoids from root of Sophora flavescens in cancer cells.

Definition

ChEBI: (2S)-2'-methoxykurarinone is a dimethoxyflavanone that is (2S)-(-)-kurarinone in which the hydroxy group at position 2' is replaced by a methoxy group. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. It has a role as a metabolite and an antineoplastic agent. It is a dimethoxyflavanone, a dihydroxyflavanone and a member of 4'-hydroxyflavanones. It is functionally related to a (2S)-(-)-kurarinone.

Properties of 2'-O-Methylkurarinone

Melting point: 112-115℃
Boiling point: 643.6±55.0 °C(Predicted)
Density  1.171±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Powder
pka 7.50±0.40(Predicted)
color  Light yellow to brown

Safety information for 2'-O-Methylkurarinone

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2'-O-Methylkurarinone

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