2-Naphthaldehyde

Synonym(s):β-Naphthaldehyde

CAS NO.：66-99-9
Empirical Formula: C11H8O
Molecular Weight: 156.18
MDL number: MFCD00004094
EINECS: 200-640-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-25 16:21:11

What is 2-Naphthaldehyde?

Chemical properties

Pink crystalline

The Uses of 2-Naphthaldehyde

2-Naphthaldehyde aids in stereo-selective formation of bicyclo 2-siloxy-2-alkoxyoxetanes. It is also used as catalytic agent and petrochemical additive.

The Uses of 2-Naphthaldehyde

2-Naphthaldehyde can be used as a reactant:

In proline catalyzed aldol reaction.
In asymmetric three-component Mannich reaction.
For the synthesis of Hantzsch 1,4-dihydropyridines.13}
Asymmetric benzoin condensation reaction.
For the synthesis of pyrazolo[1,2?b]phthalazinediones.
For the synthesis C₆₀ by flash vacuum pyrolysis.

Definition

ChEBI: A naphthaldehyde that is naphthalene substituted by a formyl group at position 2.

Synthesis Reference(s)

Synthesis, p. 470, 1996 DOI: 10.1055/s-1996-4246

Purification Methods

Distil 2-naphthaldehyde with steam then crystallise it from water or EtOH. [Beilstein 7 IV 1288.]

Properties of 2-Naphthaldehyde

Melting point:	58-61 °C (lit.)
Boiling point:	160 °C (19 mmHg)
Density	1.6211
refractive index	1.6211 (estimate)
Flash point:	160°C/19mm
storage temp.	-20°C
solubility	Chloroform, Methanol (Sparingly)
form	Powder or Chunks
color	Off-white to yellow or light beige
Water Solubility	Soluble in hot water.
FreezingPoint	1.0755
Sensitive	Air Sensitive
BRN	507750
CAS DataBase Reference	66-99-9(CAS DataBase Reference)
NIST Chemistry Reference	2-Naphthalenecarboxaldehyde(66-99-9)
EPA Substance Registry System	2-Naphthalenecarboxaldehyde (66-99-9)

Safety information for 2-Naphthaldehyde

Signal word	Warning
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..…