2-Methylbenzhydrol

CAS NO.：5472-13-9
Empirical Formula: C14H14O
Molecular Weight: 198.26
MDL number: MFCD00004490
EINECS: 226-810-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-09 19:38:33

What is 2-Methylbenzhydrol?

Chemical properties

almost white adhering powder

The Uses of 2-Methylbenzhydrol

A metabolite of the antihistaminic Orphenadrine (O695300).

Synthesis Reference(s)

Synthetic Communications, 5, p. 441, 1975 DOI: 10.1080/00397917508065578

General Description

2-Methylbenzhydrol on etherification with tropine yields tropinyl 2-methyl-benzhydryl ether hydrobromide (BS 6825). It also undergoes reduction in acetic acid containing iodine and aqueous hypophosphorous acid to yield diphenylmethanes.

Properties of 2-Methylbenzhydrol

Melting point:	93-95 °C (lit.)
Boiling point:	323 °C (lit.)
Density	1.0074 (rough estimate)
refractive index	1.5381 (estimate)
Flash point:	323°C
storage temp.	Sealed in dry,Room Temperature
solubility	Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly),
form	Solid
pka	13.56±0.20(Predicted)
color	White to Off-White
BRN	1952703
CAS DataBase Reference	5472-13-9(CAS DataBase Reference)
EPA Substance Registry System	Benzenemethanol, 2-methyl-.alpha.-phenyl- (5472-13-9)

Safety information for 2-Methylbenzhydrol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.