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HomeProduct name list2-Methyl-D-phenylalanine

2-Methyl-D-phenylalanine

Synonym(s):α-Me-D-Phe-OH;(R)-(+)-2-Amino-2-methyl-3-phenylpropionic acid

2-Methyl-D-phenylalanine Structural

What is 2-Methyl-D-phenylalanine?

Chemical properties

White powder

The Uses of 2-Methyl-D-phenylalanine

2-Methyl-D-phenylalanine is a derivative of D-Phenylalanine (P319410); the stereoisomer of L-Phenylalanine (P319415) used in the synthesis of Schaeffer’s acid analogs as important structures in tuberculostatic design. These analogs exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase.

The Uses of 2-Methyl-D-phenylalanine

α-Methyl-D-phenylalanine is used to prepare hippuryl-α-methylphenylalanine and hippuryl-α-methylphenyllactic acid as substrates for carboxypeptidase A. It is also used in the synthesis of high affinity tachykinin NK2 receptor antagonists.

Properties of 2-Methyl-D-phenylalanine

Melting point: 277-279 °C(Solv: acetone (67-64-1))
Boiling point: 312.8±30.0 °C(Predicted)
Density  1.166±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
form  Powder
pka 2.25±0.10(Predicted)
color  White to pale yellow
BRN  5254151
CAS DataBase Reference 17350-84-4(CAS DataBase Reference)

Safety information for 2-Methyl-D-phenylalanine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Methyl-D-phenylalanine

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