2-Methyl butyric acid
Synonym(s):NSC 7304
- CAS NO.:116-53-0
- Empirical Formula: C5H10O2
- Molecular Weight: 102.13
- MDL number: MFCD00002669
- EINECS: 204-145-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-24 21:11:45
What is 2-Methyl butyric acid?
Description
2-Methylbutyric acid has a pungent, acrid odor similar to Roquefort cheese with an acrid taste. At low dilutions, it has a pleasant fruity taste. May be prepared by decarboxylation of methyl ethyl malonic acid (with heat); also by oxidation of fermentation amyl alcohol (fusel oil).
Chemical properties
clear colorless to pale yellowish liquid
Chemical properties
2-Methylbutyric acid has a pungent, acrid odor similar to Roquefort cheese with an acrid taste. At low dilutions, it has a pleasant, fruity taste. Slightly soluble in water, soluble in alcohol and oils. Also soluble in Propylene glycol and poorly soluble in Glycerin.
Occurrence
Occurring as the d-, l-, and dl-isomers; the racemic form has been reported found in angelica root oil and coffee; the d-isomer in the ester form has been identified in lavender oil. Also reported found in apple, apricot, berries, grapes, papaya, peach, guava, pineapple, potato, bell pepper, tomato, peppermint and spearmint oil, vinegar, wheat breads, cheeses, chicken, mutton, pork, hop oil, beer, cognac, rum, whiskies, cider, cocoa, coffee, tea, peanuts, passion fruit, trassi, mango, plum, tamarind, rice, corn oil, loquat, scallops, Chinese quince, maté, mammee apple and Roman chamomile oil, cranberry, grape brandy, oriental tobacco, and strawberry
The Uses of 2-Methyl butyric acid
Used in the synthesis of 2-methylbutyric anhydride
The Uses of 2-Methyl butyric acid
2-Methylbutyric acid, can be used as food additive for butter, cream, cheese flavor deployment. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff. It is also used in the synthesis of 2-methylbutyric anhydride.
The Uses of 2-Methyl butyric acid
2-Methylbutyric acid was used in the synthesis of 2-methylbutyric anhydride, an acylating agent.
What are the applications of Application
2-Methylbutyric acid is used in the synthesis of 2-methylbutyric anhydride
Definition
ChEBI: A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria.
Preparation
By decarboxylation of methyl ethyl malonic acid (with heat); also by oxidation of fermentation amyl alcohol (fusel oil).
Aroma threshold values
Detection: 10 to 60 ppb. Aroma characteristics at 1.0%: acidic sour, pungent, ripe fruit leather, lingonberry, dirty cheesy, fermented pineapple fruity with a woody nuance
Taste threshold values
Taste characteristics at 10 ppm: dirty, acidic sour, ripe fruity, with a dairy buttery and cheesy nuance
General Description
Enantioselective esterification of (+/-)-2-methylbutynic acid catalyzed by Chromobacterium viscosum lipase immobilized in microemulsion-based organogels has been investigated.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Taste at 10 ppm
Properties of 2-Methyl butyric acid
Melting point: | -70 °C |
Boiling point: | 176-177 °C (lit.) |
Density | 0.936 g/mL at 25 °C (lit.) |
vapor pressure | 0.5 mm Hg ( 20 °C) |
refractive index | n |
FEMA | 2695 | 2-METHYLBUTYRIC ACID |
Flash point: | 165 °F |
storage temp. | Sealed in dry,Room Temperature |
solubility | 20g/l |
form | Liquid |
pka | 4.8(at 25℃) |
color | Clear colorless to pale yellow |
Odor | at 10.00 % in propylene glycol. pungent acid roquefort cheese |
explosive limit | 1.6-7.3%(V) |
Water Solubility | 45 g/L (20 ºC) |
JECFA Number | 255 |
BRN | 1720486 |
CAS DataBase Reference | 116-53-0(CAS DataBase Reference) |
NIST Chemistry Reference | Butanoic acid, 2-methyl-(116-53-0) |
EPA Substance Registry System | 2-Methylbutyric acid (116-53-0) |
Safety information for 2-Methyl butyric acid
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H290:Corrosive to Metals H314:Skin corrosion/irritation |
Precautionary Statement Codes |
P234:Keep only in original container. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Methyl butyric acid
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