2-methyl-1,3-thiazole-5-carboxylic acid
- CAS NO.：40004-69-1
- Empirical Formula: C5H5NO2S
- Molecular Weight: 143.16
- MDL number: MFCD01760300
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-17 21:30:02
What is 2-methyl-1,3-thiazole-5-carboxylic acid?
Synthesis
To a stirred solution of 2-methyl-thiazole-5-carboxylic acid ethyl ester (1.3 g, 8.0 mmol) in dioxane (12 mL) at room temperature was added NaOH (2N, 12 mL). After 1 h the reaction mixture was neutralized with HCl (IN, 12 mL), then filtered and the collected solid dried in vacuo to give 2-methyl-1,3-thiazole-5-carboxylic acid (758 mg, 70percent) as an off white solid.
Properties of 2-methyl-1,3-thiazole-5-carboxylic acid
| Melting point: | 209 °C(Solv: water (7732-18-5)) |
| Boiling point: | 301.2±15.0 °C(Predicted) |
| Density | 1.418±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 3.78±0.10(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C5H5NO2S/c1-3-6-2-4(9-3)5(7)8/h2H,1H3,(H,7,8) |
Safety information for 2-methyl-1,3-thiazole-5-carboxylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-methyl-1,3-thiazole-5-carboxylic acid
| InChIKey | QCXCIYPOMMIBHO-UHFFFAOYSA-N |
| SMILES | S1C(C(O)=O)=CN=C1C |
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![ETHYL 4-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBOXYLATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB9121717.gif)
![4-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBOXYLIC ACID](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2191698.gif)
![Ethyl 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylate](https://img.chemicalbook.in/CAS/GIF/175277-03-9.gif)
You may like
-
40004-69-1 2-methylthiazole-5-carboxylic acid 98%View Details
40004-69-1 -
2-Methylthiazole-5-carboxylic Acid CAS 40004-69-1View Details
40004-69-1 -
2-Methyl-1,3-thiazole-5-carboxylic acid CAS 40004-69-1View Details
40004-69-1 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1 -
733039-20-8 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 98+View Details
733039-20-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.