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HomeProduct name list2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

Synonym(s):5-METHOXY-2- BENZIMIDAZOLETHIOL;5-Methoxy-2-benzimidazolethiol

  • CAS NO.:37052-78-1
  • Empirical Formula: C8H8N2OS
  • Molecular Weight: 180.23
  • MDL number: MFCD00134581
  • EINECS: 253-326-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Structural

What is 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE?

Chemical properties

off-white to light yellowish-brown powder

The Uses of 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

Reagent used in the synthesis of COX-2 inhibitors

The Uses of 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

The Uses of 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.

What are the applications of Application

5-Methoxy-2-benzimidazolethiol is a benzimidazole

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Flammability and Explosibility

Not classified

Chemical properties

2-Mercapto-5-methoxybenzimidazole is a white or off-white crystal or powder that changes color easily under light. This product is soluble in alkali solution, slightly soluble in ethanol, and insoluble in water. Melting point: 240.0~244.0℃.

Properties of 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

Melting point: 261-263 °C(lit.)
Boiling point: 309.4±44.0 °C(Predicted)
Density  1.2425 (rough estimate)
vapor pressure  0.001Pa at 25℃
refractive index  1.5690 (estimate)
storage temp.  2-8°C
solubility  DMSO (Slightly), Methanol (Sparingly)
pka 10.13±0.30(Predicted)
form  Powder
color  Off-white to light yellow-brown
Water Solubility  insoluble
Sensitive  Air Sensitive
BRN  3605123
CAS DataBase Reference 37052-78-1(CAS DataBase Reference)

Safety information for 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

Abamectin manufacturer

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