2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Synonym(s):5-METHOXY-2- BENZIMIDAZOLETHIOL;5-Methoxy-2-benzimidazolethiol
- CAS NO.:37052-78-1
- Empirical Formula: C8H8N2OS
- Molecular Weight: 180.23
- MDL number: MFCD00134581
- EINECS: 253-326-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE?
Chemical properties
off-white to light yellowish-brown powder
The Uses of 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Reagent used in the synthesis of COX-2 inhibitors
The Uses of 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.
The Uses of 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.
What are the applications of Application
5-Methoxy-2-benzimidazolethiol is a benzimidazole
General Description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Flammability and Explosibility
Not classified
Chemical properties
2-Mercapto-5-methoxybenzimidazole is a white or off-white crystal or powder that changes color easily under light. This product is soluble in alkali solution, slightly soluble in ethanol, and insoluble in water. Melting point: 240.0~244.0℃.
Properties of 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Melting point: | 261-263 °C(lit.) |
Boiling point: | 309.4±44.0 °C(Predicted) |
Density | 1.2425 (rough estimate) |
vapor pressure | 0.001Pa at 25℃ |
refractive index | 1.5690 (estimate) |
storage temp. | 2-8°C |
solubility | DMSO (Slightly), Methanol (Sparingly) |
pka | 10.13±0.30(Predicted) |
form | Powder |
color | Off-white to light yellow-brown |
Water Solubility | insoluble |
Sensitive | Air Sensitive |
BRN | 3605123 |
CAS DataBase Reference | 37052-78-1(CAS DataBase Reference) |
Safety information for 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Abamectin manufacturer
SHREENEEL CHEMICALS
KARPSCHEM LABORATORIES PVT. LTD.
Everest Organics Limited
Finornic Chemicals (India) Private Limited
Elixir Pharma
Ebenezer Industries
Ralington Pharma
Lavybens Pharma
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