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HomeProduct name list2'-Hydroxy-3-phenylpropiophenone

2'-Hydroxy-3-phenylpropiophenone

  • CAS NO.:3516-95-8
  • Empirical Formula: C15H14O2
  • Molecular Weight: 226.27
  • MDL number: MFCD00002221
  • EINECS: 222-521-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:57
2'-Hydroxy-3-phenylpropiophenone Structural

What is 2'-Hydroxy-3-phenylpropiophenone?

Chemical properties

Slightly Yellow Crystals

The Uses of 2'-Hydroxy-3-phenylpropiophenone

A metabolite of Propafenone (P757500).

The Uses of 2'-Hydroxy-3-phenylpropiophenone

2’-Hydroxy-3-phenylpropiophenone (Propafenone EP Impurity A; Propafenone BP Impurity A; Propafenone USP Impurity A) is a metabolite of Propafenone (P757500).

General Description

2′-Hydroxy-3-phenylpropiophenone is a colorless to yellow liquid or solid. 2′-Hydroxy-3-phenylpropiophenone derivatives show antiarrhythmic,spasmolytic and local anaesthetic activities.

Properties of 2'-Hydroxy-3-phenylpropiophenone

Melting point: 36-37 °C(lit.)
Boiling point: 158°C/2mmHg(lit.)
Density  1.150±0.06 g/cm3(Predicted)
refractive index  n20/D 1.5968(lit.)
Flash point: >230 °F
storage temp.  Refrigerator
solubility  Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Eth
form  Solid
pka 8.07±0.30(Predicted)
color  Off-White Low Melting
λmax 324nm(MeOH)(lit.)
CAS DataBase Reference 3516-95-8(CAS DataBase Reference)
EPA Substance Registry System 1-Propanone, 1-(2-hydroxyphenyl)-3-phenyl- (3516-95-8)

Safety information for 2'-Hydroxy-3-phenylpropiophenone

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2'-Hydroxy-3-phenylpropiophenone

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