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HomeProduct name list2-(DIFLUOROMETHOXY)BENZALDEHYDE

2-(DIFLUOROMETHOXY)BENZALDEHYDE

2-(DIFLUOROMETHOXY)BENZALDEHYDE Structural

What is 2-(DIFLUOROMETHOXY)BENZALDEHYDE?

The Uses of 2-(DIFLUOROMETHOXY)BENZALDEHYDE

2-(Difluoromethoxy)benzaldehyde is an important raw material used as an intermediate in the preparation of pharmaceuticals, agrochemicals, and dyestuffs. It is also involved in the preparation of 4-(2-difluoromethoxyphenyl)- substituted 1,4-dihydropyridine 3,5-diesters.

The Uses of 2-(DIFLUOROMETHOXY)BENZALDEHYDE

2-(Difluoromethoxy)benzaldehyde may be used as a starting reagent in the synthesis of the following compounds:

  • 2-[2-(difluoromethoxy)benzylidene]methyl acetoacetate
  • 3-(2-cyanoethyl) 5-(2-propoxyethyl) 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
  • 2-propoxyethyl 5-cyano-4-[2-(difluoromethoxy)phenyl]-2-methyl-6-thioxo-1,4,5,6-tetrahydropyridine-3-carboxylate
  • methyl 5-cyano-4-(2-difluoromethoxyphenyl)-2-methyl-6-thioxo-1,4,5,6-tetrahydropyridine-3-carboxylate

General Description

2-(Difluoromethoxy)benzaldehyde is an ortho-difluoromethoxy substituted benzaldehyde.

Properties of 2-(DIFLUOROMETHOXY)BENZALDEHYDE

Boiling point: 216 °C (lit.)
Density  1.3 g/mL at 25 °C (lit.)
refractive index  n20/D 1.497(lit.)
Flash point: 224 °F
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  Miscible with 2-propanol and acetic acid.
form  clear liquid
color  Colorless to Light yellow to Light orange
Sensitive  Air Sensitive
BRN  389068
CAS DataBase Reference 71653-64-0(CAS DataBase Reference)

Safety information for 2-(DIFLUOROMETHOXY)BENZALDEHYDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 2-(DIFLUOROMETHOXY)BENZALDEHYDE

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