2'-Deoxyguanosine-5'-triphosphate trisodium salt
Synonym(s):dGTP-Na3
- CAS NO.:93919-41-6
- Empirical Formula: C10H17N5NaO13P3
- Molecular Weight: 531.18
- MDL number: MFCD01632476
- EINECS: 300-026-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 18:09:03
What is 2'-Deoxyguanosine-5'-triphosphate trisodium salt?
Description
2′-Deoxyguanosine 5′-triphosphate (dGTP) is made of a guanine nucleobase attached to deoxyribose and a 5′-hydroxyl on the sugar linked to a chain of three phosphate residues. It is used by the cells for the synthesis of DNA with the help of DNA polymerase.
Chemical properties
White amorphous powder
The Uses of 2'-Deoxyguanosine-5'-triphosphate trisodium salt
2′-Deoxyguanosine 5′-triphosphate trisodium salt is utilized for methods such as DNA sequencing, PCR and other DNA polymerase based DNA synthesis and repair techniques.
General Description
dGTP, PCR Grade, is a 100 mM clear, colorless solution of the sodium salt (pH 8.3). PCR Grade nucleotides from Roche are specially manufactured and purified to the highest possible chemical purity. PCR Grade nucleotides contain at least 99% of the relevant deoxynucleoside-triphosphate (dNTP) and less than 0.9% deoxynucleoside-diphosphate (dNDP).
Biochem/physiol Actions
2′-Deoxyguanosine 5′-triphosphate is used in vivo synthesis for the synthesis of DNA via DNA polymerases.
storage
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Properties of 2'-Deoxyguanosine-5'-triphosphate trisodium salt
Melting point: | >0°C |
storage temp. | -20°C |
solubility | PBS (pH 7.2): 5 mg/mL |
form | solid |
color | colorless |
CAS DataBase Reference | 93919-41-6(CAS DataBase Reference) |
Safety information for 2'-Deoxyguanosine-5'-triphosphate trisodium salt
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2'-Deoxyguanosine-5'-triphosphate trisodium salt
InChIKey | IWGGLKOTEOCWQP-BQHLMXRXSA-K |
SMILES | O=C1NC(N)=NC2N([C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O3)C=NC1=2.[NaH] |&1:8,10,12,r| |
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