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HomeProduct name list2'-Deoxyguanosine-5'-triphosphate trisodium salt

2'-Deoxyguanosine-5'-triphosphate trisodium salt

Synonym(s):dGTP-Na3

  • CAS NO.:93919-41-6
  • Empirical Formula: C10H17N5NaO13P3
  • Molecular Weight: 531.18
  • MDL number: MFCD01632476
  • EINECS: 300-026-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-17 16:00:36
2'-Deoxyguanosine-5'-triphosphate trisodium salt Structural

What is 2'-Deoxyguanosine-5'-triphosphate trisodium salt?

Description

2′-Deoxyguanosine 5′-triphosphate (dGTP) is made of a guanine nucleobase attached to deoxyribose and a 5′-hydroxyl on the sugar linked to a chain of three phosphate residues. It is used by the cells for the synthesis of DNA with the help of DNA polymerase.

Chemical properties

White amorphous powder

The Uses of 2'-Deoxyguanosine-5'-triphosphate trisodium salt

2′-Deoxyguanosine 5′-triphosphate trisodium salt is utilized for methods such as DNA sequencing, PCR and other DNA polymerase based DNA synthesis and repair techniques.

General Description

dGTP, PCR Grade, is a 100 mM clear, colorless solution of the sodium salt (pH 8.3). PCR Grade nucleotides from Roche are specially manufactured and purified to the highest possible chemical purity. PCR Grade nucleotides contain at least 99% of the relevant deoxynucleoside-triphosphate (dNTP) and less than 0.9% deoxynucleoside-diphosphate (dNDP).

Biochem/physiol Actions

2′-Deoxyguanosine 5′-triphosphate is used in vivo synthesis for the synthesis of DNA via DNA polymerases.

storage

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Properties of 2'-Deoxyguanosine-5'-triphosphate trisodium salt

Melting point: >0°C
storage temp.  -20°C
solubility  PBS (pH 7.2): 5 mg/mL
form  solid
color  colorless
CAS DataBase Reference 93919-41-6(CAS DataBase Reference)

Safety information for 2'-Deoxyguanosine-5'-triphosphate trisodium salt

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2'-Deoxyguanosine-5'-triphosphate trisodium salt

InChIKey IWGGLKOTEOCWQP-BQHLMXRXSA-K
SMILES O=C1NC(N)=NC2N([C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O3)C=NC1=2.[NaH] |&1:8,10,12,r|

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