2-Chlorothiophene
Synonym(s):2-Thienyl chloride
- CAS NO.:96-43-5
- Empirical Formula: C4H3ClS
- Molecular Weight: 118.58
- MDL number: MFCD00005421
- EINECS: 202-505-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 15:18:15
What is 2-Chlorothiophene?
Chemical properties
Colorless to light yellow liquid
The Uses of 2-Chlorothiophene
2-Chlorothiophene was used in the preparation of 5-phenylthiophene derivative.
What are the applications of Application
2-Chlorothiophene is a heterocyclic compound that belongs to the group of organic compounds called thiophenes. It is an effective analgesic and anti-inflammatory drug that has been used in the treatment of inflammatory bowel disease. 2-Chlorothiophene is used as a reagent in chemical synthesis, especially the preparation of pharmaceutical preparations. This compound can be prepared by photoelectron or hydrochloric acid. The suzuki coupling reaction with pyrimidine compounds is another method for synthesizing this compound.
General Description
The photodissociation dynamics of 2-chlorothiophene was studied using resonance enhanced multiphoton ionization (REMPI) time-of-flight (TOF) technique.
Purification Methods
Purify it by fractional distillation at atmospheric pressure or by gas chromatography. [Conde et al. Synthesis 412 1976, Beilstein 17/1 V 303.]
Properties of 2-Chlorothiophene
Melting point: | -71.9 °C |
Boiling point: | 127-129 °C (lit.) |
Density | 1.286 g/mL at 25 °C (lit.) |
refractive index | n |
Flash point: | 73 °F |
storage temp. | 2-8°C |
solubility | soluble in Chloroform |
form | Liquid |
color | Clear colorless to light brown |
Specific Gravity | 1.286 |
Water Solubility | INSOLUBLE |
BRN | 104652 |
Stability: | Volatile |
CAS DataBase Reference | 96-43-5(CAS DataBase Reference) |
NIST Chemistry Reference | Thiophene, 2-chloro-(96-43-5) |
EPA Substance Registry System | Thiophene, 2-chloro- (96-43-5) |
Safety information for 2-Chlorothiophene
Signal word | Warning |
Pictogram(s) |
Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H225:Flammable liquids H226:Flammable liquids H301:Acute toxicity,oral H302:Acute toxicity,oral H311:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-Chlorothiophene
InChIKey | GSFNQBFZFXUTBN-UHFFFAOYSA-N |
Abamectin manufacturer
Aether Industries Limited
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