2-CHLOROPHENYLZINC IODIDE

CAS NO.：148651-35-8
Empirical Formula: C6H4ClIZn
Molecular Weight: 303.84
MDL number: MFCD01863648
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-27 08:28:43

What is 2-CHLOROPHENYLZINC IODIDE?

The Uses of 2-CHLOROPHENYLZINC IODIDE

2-Chlorophenylzinc iodide is an organozinc compound, which can be used as a reactant in Negishi cross-coupling reaction to construct carbon-carbon bonds by reacting with organic halides using nickel or palladium catalysts.
It can also be utilized as a reactant to prepare:

Arylmethanes via rhodium-catalyzed cross-coupling reaction with methyl halides.
(2-chlorobenzyl)trimethylsilane by Rh-catalyzed cross-coupling reaction with (iodomethyl)trimethylsilane.
Dichloro biphenyl by palladium catalyzed oxidative homocoupling reaction using N-chlorosuccinimide (NCS) or O₂ as the oxidant.

Properties of 2-CHLOROPHENYLZINC IODIDE

Density	0.973 g/mL at 25 °C
Flash point:	1 °F
storage temp.	2-8°C
Sensitive	Air & Light Sensitive
Exposure limits	ACGIH: TWA 50 ppm; STEL 100 ppm (Skin) OSHA: TWA 200 ppm(590 mg/m3) NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)
CAS DataBase Reference	148651-35-8

Safety information for 2-CHLOROPHENYLZINC IODIDE

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H225:Flammable liquids H261:Substances And Mixtures Which, In Contact With Water,Emit Flammable Gases H302:Acute toxicity,oral H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H333:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P223:Keep away from any possible contact with water, because of violent reaction and possible flash fire. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool.