2-Chloromethyl-3,4-dimethoxypyridinium chloride

CAS NO.：72830-09-2
Empirical Formula: C8H11Cl2NO2
Molecular Weight: 224.08
MDL number: MFCD02181083
EINECS: 416-440-5
SAFETY DATA SHEET (SDS)
Update Date: 2025-04-29 17:45:46

What is 2-Chloromethyl-3,4-dimethoxypyridinium chloride?

Chemical properties

Light Brown Solid

The Uses of 2-Chloromethyl-3,4-dimethoxypyridinium chloride

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride may be used as a precursor for the preparation [(2-pyridyl)-2-ethyl]-[3,4-dimethoxy-(2-pyridylmethyl)]-N-methylamine.

General Description

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride (CDP) can be synthesized using maltol as a starting material. CDP and DMS (dimethyl sulfate) are used in the preparation of pantoprazole sodium (PPS), an antiulcerative drug. The quantification of CDP and DMS in PPS can be done simultaneously by gas chromatography–mass spectrometry (GC-MS) method.

Properties of 2-Chloromethyl-3,4-dimethoxypyridinium chloride

Melting point:	155 °C (dec.)(lit.)
storage temp.	Inert atmosphere,Room Temperature
Water Solubility	Soluble in water
solubility	Chloroform (Slightly, Heated), Methanol (Very Slightly)
form	powder to crystal
color	White to Orange to Green
BRN	5360726
CAS DataBase Reference	72830-09-2(CAS DataBase Reference)

Safety information for 2-Chloromethyl-3,4-dimethoxypyridinium chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.