2-CHLOROLEPIDINE
Synonym(s):2-Chloro-4-methylquinoline;2-Chlorolepidine
- CAS NO.：634-47-9
- Empirical Formula: C10H8ClN
- Molecular Weight: 177.63
- MDL number: MFCD00006742
- EINECS: 211-209-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-27 16:27:43
What is 2-CHLOROLEPIDINE?
Chemical properties
white to light yellow crystal powder
The Uses of 2-CHLOROLEPIDINE
2-Chloro-4-methyl-quinoline is a useful synthetic intermediate. It is an intermediate used to synthesize 4-Methyl-2-(1-piperidinyl)-quinoline (M320715) which is a potent inhibitor of TRPC4 channels, responsible for various stimulation, muscle response due to interaction with the environment. 2-Chloro-4-methyl-quinoline is also considered as a cyanine dye.
Synthesis Reference(s)
Journal of the American Chemical Society, 63, p. 2367, 1941 DOI: 10.1021/ja01854a016
Organic Syntheses, Coll. Vol. 3, p. 194, 1955
Properties of 2-CHLOROLEPIDINE
| Melting point: | 55-58 °C(lit.) |
| Boiling point: | 296 °C(lit.) |
| Density | 1.1810 (rough estimate) |
| refractive index | 1.6224 (estimate) |
| Flash point: | 296°C |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 0.98±0.50(Predicted) |
| color | White to Almost white |
| BRN | 118333 |
| CAS DataBase Reference | 634-47-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Quinoline, 2-chloro-4-methyl-(634-47-9) |
Safety information for 2-CHLOROLEPIDINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-CHLOROLEPIDINE
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product: 634-47-9 2-Chlorolepidine 98%
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