2-CHLOROLEPIDINE

Synonym(s):2-Chloro-4-methylquinoline;2-Chlorolepidine

CAS NO.：634-47-9
Empirical Formula: C10H8ClN
Molecular Weight: 177.63
MDL number: MFCD00006742
EINECS: 211-209-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-27 16:27:43

What is 2-CHLOROLEPIDINE?

Chemical properties

white to light yellow crystal powder

The Uses of 2-CHLOROLEPIDINE

2-Chloro-4-methyl-quinoline is a useful synthetic intermediate. It is an intermediate used to synthesize 4-Methyl-2-(1-piperidinyl)-quinoline (M320715) which is a potent inhibitor of TRPC4 channels, responsible for various stimulation, muscle response due to interaction with the environment. 2-Chloro-4-methyl-quinoline is also considered as a cyanine dye.

Synthesis Reference(s)

Journal of the American Chemical Society, 63, p. 2367, 1941 DOI: 10.1021/ja01854a016
Organic Syntheses, Coll. Vol. 3, p. 194, 1955

Properties of 2-CHLOROLEPIDINE

Melting point:	55-58 °C(lit.)
Boiling point:	296 °C(lit.)
Density	1.1810 (rough estimate)
refractive index	1.6224 (estimate)
Flash point:	296°C
storage temp.	Inert atmosphere,Room Temperature
form	powder to crystal
pka	0.98±0.50(Predicted)
color	White to Almost white
BRN	118333
CAS DataBase Reference	634-47-9(CAS DataBase Reference)
NIST Chemistry Reference	Quinoline, 2-chloro-4-methyl-(634-47-9)

Safety information for 2-CHLOROLEPIDINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.