2-CHLORO-4'-HYDROXYACETOPHENONE
- CAS NO.:6305-04-0
- Empirical Formula: C8H7ClO2
- Molecular Weight: 170.59
- MDL number: MFCD00229893
- EINECS: 228-613-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-08-14 17:23:18
What is 2-CHLORO-4'-HYDROXYACETOPHENONE?
The Uses of 2-CHLORO-4'-HYDROXYACETOPHENONE
2-Chloro-1-(4-hydroxy-phenyl)-ethanone is a reagent that is used in the preparation of hydroxypyrimidine derivatives and their HDAC (histone deacetylases) inhibitory activity.
Preparation
Also obtained by reaction of acetyl chloride with anisole in the presence of aluminium chloride in n-heptane at 35° for 4 h 30 min (20%).
Properties of 2-CHLORO-4'-HYDROXYACETOPHENONE
Melting point: | 145-146 °C |
Boiling point: | 241.44°C (rough estimate) |
Density | 1.2315 (rough estimate) |
refractive index | 1.5100 (estimate) |
pka | 7.72±0.15(Predicted) |
CAS DataBase Reference | 6305-04-0(CAS DataBase Reference) |
EPA Substance Registry System | Ethanone, 2-chloro-1-(4-hydroxyphenyl)- (6305-04-0) |
Safety information for 2-CHLORO-4'-HYDROXYACETOPHENONE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-CHLORO-4'-HYDROXYACETOPHENONE
New Products
Tubulysin E Tubulysin G Tubulysin I Tubulysin H 2,2-Difluoropropanol CYCLOBUTYLAMINE HYDROCHLORIDE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 4-(Benzyloxy)-3-bromophenylacetic Acid tetrahydro-4-methyl-2H-pyran Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate Fuel shell (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Calcium Sodium Phosphosilicate IH (1S,4S)-4- (3,4-dichlorophenyl) -N-methyl-1,2,3,4- tetrahydrona phthalen -1-amine .D-Mandelate 4-(2-fluoro-4- nitrophenyl) thiomorpholine Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
Ethanone, 2-chloro-1-(3,5-dihydroxyphenyl)-
Apremilast Impurity 4
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
(R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
APST-ZA
Apremilast
(S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
6H,12H-Indazolo[2,1-a]indazole-1,7-dicarboxylic acid, 6,12-dioxo-
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