2-Chloro-4-fluorobenzoic acid

CAS NO.：2252-51-9
Empirical Formula: C7H4ClFO2
Molecular Weight: 174.56
MDL number: MFCD00010615
EINECS: 218-845-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-05 20:55:42

What is 2-Chloro-4-fluorobenzoic acid?

Chemical properties

Powder or crystalline or flakes

The Uses of 2-Chloro-4-fluorobenzoic acid

2-Chloro-4-fluorobenzoic acid was used in the preparation of 2-(2-chloro-4-fluorophenyl)-benzothiazole.

What are the applications of Application

2-Chloro-4-fluorobenzoic acid can be used as:
(1) Studies on the preparation, luminescence and thermal properties of lanthanide complexes of 2-chloro-4-fluorobenzoic acid.
(2) Preparation, crystal structure, thermal and fluorescence property studies of rare earth complexes composed with 2,2':6′,2″-tripyridine.
(3) Analysis of charge density of intermolecular interactions between isohalogen (Cl--F) and homohalogen (F--F) molecules in molecular crystals. Attractive intermolecular Cl--F interactions (type II interactions) in 2-chloro-4-fluorobenzoic acid.

Properties of 2-Chloro-4-fluorobenzoic acid

Melting point:	181-183 °C (lit.)
Boiling point:	271.9±20.0 °C(Predicted)
Density	1.4016 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	95% ethanol: soluble50mg/mL, clear to very slightly hazy, colorless to very faintly yellow
form	Powder or Flakes
pka	2.90±0.25(Predicted)
color	White
BRN	1946215
InChI	InChI=1S/C7H4ClFO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,(H,10,11)
CAS DataBase Reference	2252-51-9(CAS DataBase Reference)
NIST Chemistry Reference	2-Chloro-4-fluorobenzoic acid(2252-51-9)
EPA Substance Registry System	Benzoic acid, 2-chloro-4-fluoro- (2252-51-9)

Safety information for 2-Chloro-4-fluorobenzoic acid

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.