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HomeProduct name list2-Chloro-4-amino-6,7-dimethoxyquinazoline

2-Chloro-4-amino-6,7-dimethoxyquinazoline

Synonym(s):2-Chloro-6,7-dimethoxy-4-quinazolinamine;4-Amino-2-chloro-6,7-dimethoxyquinazoline

  • CAS NO.:23680-84-4
  • Empirical Formula: C10H10ClN3O2
  • Molecular Weight: 239.66
  • MDL number: MFCD00051734
  • EINECS: 245-821-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-08 17:36:13
2-Chloro-4-amino-6,7-dimethoxyquinazoline Structural

What is 2-Chloro-4-amino-6,7-dimethoxyquinazoline?

Chemical properties

Off-White Solid

The Uses of 2-Chloro-4-amino-6,7-dimethoxyquinazoline

Intermediate in the production on Terazosin.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 20, p. 146, 1977 DOI: 10.1021/jm00211a031

Flammability and Explosibility

Non flammable

Properties of 2-Chloro-4-amino-6,7-dimethoxyquinazoline

Melting point: 262-268 °C (dec.)(lit.)
Boiling point: 374.0±42.0 °C(Predicted)
Density  1.5062 (rough estimate)
vapor pressure  0Pa at 25℃
refractive index  1.5500 (estimate)
storage temp.  2-8°C
solubility  DMSO (Sparingly, Heated), Methanol (Slightly, Heated)
form  neat
pka 4.35±0.30(Predicted)
color  White to Off-White
Water Solubility  1.418g/L at 25℃
BRN  747463
CAS DataBase Reference 23680-84-4(CAS DataBase Reference)
NIST Chemistry Reference 4-Amino-2-chloro-6,7-dimethoxyquinazoline(23680-84-4)

Safety information for 2-Chloro-4-amino-6,7-dimethoxyquinazoline

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Chloro-4-amino-6,7-dimethoxyquinazoline

2-Chloro-4-amino-6,7-dimethoxyquinazoline manufacturer

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