2-Bromo-6-nitrophenol
- CAS NO.：13073-25-1
- Empirical Formula: C6H4BrNO3
- Molecular Weight: 218
- MDL number: MFCD02683216
- EINECS: 629-309-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is 2-Bromo-6-nitrophenol?
Chemical properties
White solid
The Uses of 2-Bromo-6-nitrophenol
2-Bromo-6-nitrophenol is an intermediate used in the synthesis of N-Hydroxy Eltrombopag (H825795), which is a derivative compound of Eltrombopag (508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
Preparation
2-Bromo-6-nitrophenol can be prepared by reacting ammonium formate with hydroxyl group of 2-bromo-6-nitropyridine. The reaction yield can be improved by activating the hydroxyl group and removing impurities through a dehydration reaction.
Synthesis
2-Bromo-6-nitrophenol is synthesized by coupling metal salts with nitro groups or amines, which are called Suzuki coupling reactions.
Properties of 2-Bromo-6-nitrophenol
| Melting point: | 66-70 °C (lit.) |
| Boiling point: | 227.2±20.0 °C(Predicted) |
| Density | 1.881±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform; Methanol |
| form | Solid |
| pka | 5.36±0.24(Predicted) |
| color | Yellow |
| CAS DataBase Reference | 13073-25-1(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Bromo-6-nitrophenol (13073-25-1) |
Safety information for 2-Bromo-6-nitrophenol
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-Bromo-6-nitrophenol
Abamectin manufacturer
SYNGENESIS CHEMSCIENCE PRIVATE LIMITED
1Y
Phone:+919067779401
Whatsapp: +91 9067779401
product: 2-Bromo 6-nitrophenol 13073-25-1 99%
JSK Chemicals
1Y
Phone:+919879767970
Whatsapp: +91 9879767970
product: 13073-25-1 2-Bromo-6-nitrophenol, 97% 99%
Vepan Pharmatech Pvt Ltd
1Y
Phone:+91-9966094448
Whatsapp: +91 9966094448
product: 2-Bromo-6- nitrophenol
Rivashaa Agrotech Biopharma Pvt. Ltd.
1Y
Phone:+91-7926462688
product: 2-Bromo-6-nitrophenol 13073-25-1 98%
ALS INDIA LIFE SCIENCES
1Y
Phone:+91-8977036379
Whatsapp: +91 8008166674
product: 13073-25-1 2-Bromo-6-nitrophenol 98%
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
2-bromo-6-nitrophenol 99%View Details
13073-25-1 -
2-Bromo 6-nitrophenol 13073-25-1 99%View Details
13073-25-1 -
13073-25-1 2-Bromo-6-nitrophenol 98%View Details
13073-25-1 -
13073-25-1 99%View Details
13073-25-1 -
2-Bromo-6-nitrophenol 98%View Details
13073-25-1 -
13073-25-1 2-Bromo-6-nitrophenol, 97% 99%View Details
13073-25-1 -
2-Bromo-6-nitrophenol, 97% CAS 13073-25-1View Details
13073-25-1 -
2-Bromo-6-nitrophenol CAS 13073-25-1View Details
13073-25-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.