2-AMINO-4'-BROMOACETOPHENONE HYDROCHLORIDE

CAS NO.：5467-72-1
Empirical Formula: C8H9BrClNO
Molecular Weight: 250.52
MDL number: MFCD00051998
EINECS: 226-778-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-08-18 16:53:28

What is 2-AMINO-4'-BROMOACETOPHENONE HYDROCHLORIDE?

The Uses of 2-AMINO-4'-BROMOACETOPHENONE HYDROCHLORIDE

2-Amino-4''-bromoacetophenone Hydrochloride is used as a reagent in the synthesis of Ledipasvir (L320100); a potent, once-daily oral NS5A inhibitor used for treatment of hepatitis C virus infection. 2-Amino-4''-bromoacetophenone Hydrochloride is also used in the preparation of the β-receptor agonists (-)-Denopamine (D231485) and (-)-Arbutamine (A766300).

General Description

2-Amino-4′-bromoacetophenone hydrochloride is an organic building block useful for chemical synthesis.

Properties of 2-AMINO-4'-BROMOACETOPHENONE HYDROCHLORIDE

Melting point:	285 °C (dec.)(lit.)
storage temp.	Refrigerator
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
BRN	3630035
CAS DataBase Reference	5467-72-1(CAS DataBase Reference)

Safety information for 2-AMINO-4'-BROMOACETOPHENONE HYDROCHLORIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.