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HomeProduct name list2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE

2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE

  • CAS NO.:14665-75-9
  • Empirical Formula: C8H9NO2.ClH
  • Molecular Weight: 187.625
  • MDL number: MFCD11974302
  • Update Date: 2023-04-23 13:52:06
2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Structural

What is 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE?

The Uses of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE

2-Amino-3’-hydroxy-acetophenone Hydrochloride is a reactant in the synthesis of TRPM8 modulators.

Preparation

Preparation by hydrolysis of m-(benzoyloxy)- a-amino-acetophenone hydrochloride (SM) (m.p. 202–205°) with refluxing 10% hydrochloric acid (quantitative yield), for 2 h (80%); ? with 37% hydrochloric acid in chlorobenzene at 90° for 3 h (90%). SM was obtained by reaction of hexamethylenetetramine with m-(benzoyloxy)- a-bromoacetophenone (m.p. 162°) in ethanol in the presence of 37% hydrochloric acid for 6 h at r.t. (75%).

Properties of 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE

Melting point: 221–222°C
storage temp.  Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility  DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form  Solid
color  Pale Beige to Brown

Safety information for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE

Computed Descriptors for 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE

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