2-Amino-2',5-dichlorobenzophenone
Synonym(s):2-Amino-2′,5-dichlorobenzophenone
- CAS NO.：2958-36-3
- Empirical Formula: C13H9Cl2NO
- Molecular Weight: 266.12
- MDL number: MFCD00007840
- EINECS: 220-985-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-30 18:52:02
What is 2-Amino-2',5-dichlorobenzophenone?
Chemical properties
YELLOW TO YELLOW-GREEN POWDER
The Uses of 2-Amino-2',5-dichlorobenzophenone
2-Amino-2',5-dichlorobenzophenone is used to produce lorazepam a drug of the benzodiazepine group, used especially to treat anxiety.
The Uses of 2-Amino-2',5-dichlorobenzophenone
Lorazepam Impurity A.
General Description
2-Amino-2′,5-dichlorobenzophenone can be synthesized from a precursor diazepine, Iorazepam.
Properties of 2-Amino-2',5-dichlorobenzophenone
| Melting point: | 87-89 °C(lit.) |
| Boiling point: | 453.6±40.0 °C(Predicted) |
| Density | 1.3134 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5490 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | methanol: soluble |
| pka | -0.97±0.10(Predicted) |
| form | neat |
| form | Solid |
| color | Yellow to Green |
| Water Solubility | Insoluble in water. |
| BRN | 652774 |
| CAS DataBase Reference | 2958-36-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Methanone, (2-amino-5-chlorophenyl)(2-chlorophenyl)-(2958-36-3) |
| EPA Substance Registry System | Methanone, (2-amino-5-chlorophenyl)(2-chlorophenyl)- (2958-36-3) |
Safety information for 2-Amino-2',5-dichlorobenzophenone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-2',5-dichlorobenzophenone
| InChIKey | KWZYIAJRFJVQDO-UHFFFAOYSA-N |
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